Zinc gluconate
- CAS NO.:4468-02-4
- Empirical Formula: C12H22O14Zn
- Molecular Weight: 455.68
- MDL number: MFCD00868110
- EINECS: 224-736-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-28 19:59:05
![Zinc gluconate Structural](https://img.chemicalbook.in/CAS/GIF/4468-02-4.gif)
What is Zinc gluconate?
Absorption
Please refer to DrugBank entry Zinc
Toxicity
Nausea, vomiting, diarrhea, and mouth irritation have been reported in patients ingesting zinc gluconate tablets that were dissolved in the mouth for management the common cold .
Zinc crosses the placenta and is found the cord blood and placenta. Fetal concentrations are regulated by the placenta .
For more information, refer to Please refer to DrugBank entry Zinc.
Acute: 1290 mg/kg in mouse
The Uses of Zinc gluconate
zinc gluconate helps maintain the skin in good condition and acts as a deodorant by preventing the growth of micro-organisms, such as bacteria, fungi or yeast, in a formulation. Zinc gluconate could also be effectively used in anti-acne products.
Background
Zinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA . It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Although it has been nasally administered for treating the common cold, this route of administration has been associated with some cases of anosmia , , , .
Studies show that zinc may be better absorbed in humans in the gluconate form , , however, results from other studies may vary.
Interestingly, zinc supplementation has become a critical intervention for treating diarrheal episodes in children. Studies suggest that administration of zinc along with new low osmolarity oral rehydration solutions/salts (oral rehydration solution), may reduce both the duration and severity of diarrheal episodes for up to 12 weeks .
More information about Zinc (in its natural form) is available at Zinc.
Indications
Zinc gluconate is mainly indicated in conditions like zinc deficiency, and can also be administered in adjunctive therapy as an alternative drug of choice in diarrhea .
Pharmacokinetics
Zinc is an important mineral found in almost every cell in the human body. It promotes the activity of about 100 enzymes. Zinc deficiency is often associated with an increased risk of infection. When they are used to treat the common cold, zinc supplements may interfere with rhinovirus cleavage or adhesion and may play a role in protecting plasma membranes from microbial toxins and complement .
Metabolism
Please refer to DrugBank entry Zinc
Properties of Zinc gluconate
Melting point: | 172-175 °C |
Boiling point: | 319°C |
Density | 1.44[at 20℃] |
solubility | Soluble in water, practically insoluble in anhydrous ethanol and in methylene chloride. |
form | powder to crystal |
color | White to Almost white |
Water Solubility | Soluble in water 100g/ l. |
Safety information for Zinc gluconate
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. |
Computed Descriptors for Zinc gluconate
Abamectin manufacturer
Indiana ChemPort
Gangotri Inorganic Private Limited
Kronox Lab Sciences Pvt Ltd
Salicylates and Chemicals Pvt. Ltd.
Annexe Chem Pvt Ltd
ShanPar Industries Pvt Ltd
West Bengal Chemical Industries Ltd.
New Products
3-Pyridineacrylic acid 3-Bromo-4-fluorophenol N-Boc-Ethylenediamine cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 4-Aminotetrahydropyran hydrochloride 4,5-Dibromopyridazin-3-one N-Benzyl-3-hydroxypiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-AminophenaethylalcholRelated products of tetrahydrofuran
![](https://img.chemicalbook.in/CAS/GIF/527-07-1.gif)
![](https://img.chemicalbook.in/CAS/GIF/526-95-4.gif)
![](https://img.chemicalbook.in/CAS/GIF/56329-42-1.gif)
![](https://img.chemicalbook.in/CAS/GIF/7214-08-6.gif)
![](https://img.chemicalbook.in/CAS/GIF/299-28-5.gif)
![](https://img.chemicalbook.in/CAS/GIF/527-09-3.gif)
![](https://img.chemicalbook.in/CAS/GIF/299-27-4.gif)
You may like
-
Zinc Gluconate 98%View Details
-
Zinc gluconate 98%View Details
-
4468-02-4 99%View Details
4468-02-4 -
Zinc gluconate 99%View Details
4468-02-4 -
Zinc gluconate 4468-02-4 98%View Details
4468-02-4 -
4468-02-4 Zinc gluconate 98%View Details
4468-02-4 -
4468-02-4 99%View Details
4468-02-4 -
Zinc gluconate 98%View Details
4468-02-4