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HomeProduct name listZ-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-PHE-DL-ALA-FLUOROMETHYLKETONE Structural

What is Z-PHE-DL-ALA-FLUOROMETHYLKETONE?

Description

Z-FA-FMK is an irreversible inhibitor of cysteine proteases, including cathepsins B, L, and S, cruzain, and papain. It also inhibits effector caspases-2, -3, -6, and -7 (IC50 = 6-32 μM) without affecting the initiator caspases-8 and -10. Z-FA-FMK also modulates infection by certain bacteria, parasites, and viruses. It can be used both in cells and in vivo.

The Uses of Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.

What are the applications of Application

Z-FA-FMK is inhibits effector, but not initator caspases in vitro, and suppress some forms of apoptosis

Properties of Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Boiling point: 630.5±55.0 °C(Predicted)
Density  1?+-.0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,2-8°C
solubility  DMF: 5 mg/ml; DMSO: 5 mg/ml
form  White solid
pka 11.07±0.46(Predicted)
color  White to off-white

Safety information for Z-PHE-DL-ALA-FLUOROMETHYLKETONE

Computed Descriptors for Z-PHE-DL-ALA-FLUOROMETHYLKETONE

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