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HomeProduct name listXPhos Pd G2

XPhos Pd G2

Synonym(s):2nd Generation XPhos Precatalyst;Chloro(2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II);X-Phos aminobiphenyl palladium chloride precatalyst;XPhos-Pd-G2

XPhos Pd G2 Structural

What is XPhos Pd G2?

The Uses of XPhos Pd G2

XPhos Pd G2 is a used as a catalyst in chemical reactions.

The Uses of XPhos Pd G2

XPhos Pd G2 was employed as catalyst in the following reactions:

  • Palladium-catalyzed Suzuki-Miyaura coupling reactions of potassium organotrifluoroborates and sulfamates.
  • Suzuki-Miyaura cross-coupling reactions of sensitive aryl and heteroarylboronic acids.
  • Synthesis of potassium Boc-protected secondary aminomethyltrifluoroborates, via Suzuki-Miyaura cross-coupling reaction.

General Description

XPhos Pd G2 is a bulky monodentate biaryl ligand. It is a Buchwald′s 2nd generation preformed catalyst. It undergoes rapid reductive elimination to form a reactive, monoligated Pd(0) species.

Properties of XPhos Pd G2

Melting point: 202-210°C
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
form  Powder
color  white

Safety information for XPhos Pd G2

Computed Descriptors for XPhos Pd G2

InChIKey USWOVTRTHZODCW-UHFFFAOYSA-N
SMILES C1(C2=CC=CC=C2N)=CC=CC=C1[Pd+2].C1(C2=C(C(C)C)C=C(C(C)C)C=C2C(C)C)=CC=CC(Cl)=C1P(C1CCCCC1)C1CCCCC1

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