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HomeProduct name listVatalanib base

Vatalanib base

Vatalanib base Structural

What is Vatalanib base?

The Uses of Vatalanib base

Vatalanib (PTK787) is an inhibitor of VEGFR2/KDR, Flt-1 and c-Kit with IC50 of 37 nM, 77 nM and 730 nM, respectively.

The Uses of Vatalanib base

anti-viral

Definition

ChEBI: A member of the class of phthalazines that is phthalazine in which the hydrogens at positions 1 and 4have been replaced by a p-chlorophenylamino group and a pyridin-4-ylmethyl group, respectively. It is a multi-targeted tyrosine kinase inhibit r for all isoforms of VEGFR, PDGFR and c-Kit.

Properties of Vatalanib base

Melting point: 209-212°
Boiling point: 587.8±50.0 °C(Predicted)
Density  1.330±0.06 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  ≥16.85 mg/mL in DMSO; ≥3.0125 mg/mL in EtOH with gentle warming and ultrasonic; ≥32.53 mg/mL in H2O with gentle warming and ultrasonic
form  solid
pka 5.46±0.10(Predicted)
color  Light yellow to yellow

Safety information for Vatalanib base

Computed Descriptors for Vatalanib base

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