Tripropyl orthoformate
- CAS NO.：621-76-1
- Empirical Formula: C10H22O3
- Molecular Weight: 190.28
- MDL number: MFCD00015214
- EINECS: 210-704-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-09-25 17:15:13
What is Tripropyl orthoformate?
Chemical properties
clear colorless liquid
The Uses of Tripropyl orthoformate
Tripropyl orthoformate was used as alcohol donor to investigate the activity and enantioselectivity of Novozym 435 in the esterification of rac-fenoprofen in methylcyclohexane. It may be used as a drying agent during the synthesis of squaraine derivatives.
The Uses of Tripropyl orthoformate
Tripropoxymethane can be used in the lipase-?catalyzed esterification aimed at the kinetic resolution of racemic acids, circumventing the adverse effects of the water formed in the course of the reaction.
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 3801, 1955 DOI: 10.1021/ja01619a036
General Description
Gas phase reactions of the rare earth metal cations with tripropyl orthoformate were studied by Fourier transform ion cyclotron resonance mass spectrometry.
Properties of Tripropyl orthoformate
| Boiling point: | 106-108 °C/40 mmHg (lit.) |
| Density | 0.883 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 162 °F |
| form | Liquid |
| color | Clear colorless |
| Specific Gravity | 0.883 |
| Sensitive | Moisture Sensitive |
| BRN | 1744249 |
| CAS DataBase Reference | 621-76-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Tripropyl orthoformate(621-76-1) |
| EPA Substance Registry System | Tripropyl orthoformate (621-76-1) |
Safety information for Tripropyl orthoformate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tripropyl orthoformate
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