TMPYP
Synonym(s):meso-5,10,15,20-Tetrakis-(N-methyl-4-pyridyl)porphine, Tetratosylate;meso-Tetra(N-methyl-4-pyridyl)porphine tetratosylate salt;TMPyP;TMPyP4 - CAS 36951-72-1 - Calbiochem
- CAS NO.：36951-72-1
- Empirical Formula: C72H66N8O12S4
- Molecular Weight: 1363.6
- MDL number: MFCD00013468
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is TMPYP?
The Uses of TMPYP
TMPyP4 is a potent inhibitor of telomerase activity.
What are the applications of Application
TMPyP4 is a potent inhibitor of telomerase activity
Definition
ChEBI: An organosulfonate salt that is the tetrakis(p-toluenesulfonate) salt of meso-tetrakis(N-methyl-4-pyridyl)porphine.
General Description
5,10,15,20-Tetrakis(1-methyl-4-pyridinio)porphyrin tetra(p toluenesulfonate) (TMPyP) is a positively charged, two-photon dye, that can bind to DNA in cell cultures and affect the cell viability. Long term encapsulation of TMPyP by nanoparticles is reported to prevent the dye from direct contact with cells, but the dye can still kill the cells via singlet-oxygen production on exposure to infrared light. Nanostructured catalyst of platinum nanoparticles supported on TMPyP functionalized graphene is prepared by hydrothermal polyol process. TMPyP is reported to show excellent 1O2 luminescence signals on incubation with the fungus, Candida albicans. On photoexcitation, TMPyP undergoes charge-transfer interaction with chemically reduced graphene oxide. It is also reported to be a promising photodynamic therapy photosensitizer.
storage
Store at +4°C
Properties of TMPYP
| Melting point: | >300℃ |
| storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
| solubility | water: soluble50MM(lit.) |
| form | Purple solid |
| color | Dark red to Dark purple to Dark blue |
| Water Solubility | Soluble to 50 mM in water |
| BRN | 6049195 |
| Stability: | Hygroscopic, Light Sensitive |
Safety information for TMPYP
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for TMPYP
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