Tetrazolium Blue Chloride

Synonym(s):3,3′-(3,3′-Dimethoxy[1,1′-biphenyl]-4,4′-diyl)-bis(2,5-diphenyl-2H-tetrazolium) dichloride;3,3′-Dianisole-4,4′-bis(3,5-diphenyltetrazolium chloride);Blue Tetrazolium chloride;BTC;TZ

CAS NO.：1871-22-3
Empirical Formula: C40H32Cl2N8O2
Molecular Weight: 727.64
MDL number: MFCD00040933
EINECS: 217-488-8
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is Tetrazolium Blue Chloride?

Chemical properties

yellow crystalline solid

The Uses of Tetrazolium Blue Chloride

Tetrazolium Blue Chloride is used for its anti-plasmodium activity. Also used in the study of inhibition of diphenyltetrazolium bromide (MTT) reduction by β-amyloid peptides resulting in neurodegenerative manifestations. Dyes and metabolites.

The Uses of Tetrazolium Blue Chloride

For research in seed germination, as stain for bacteria and molds, in histochemical studies, to demonstrate oxidation-reduction enzymes in normal and cancerous tissues. See also Triphenyltetrazolium Chloride.

What are the applications of Application

Tetrazolium Blue Chloride is a useful compound in the prepartion of DNA cation complexes

Definition

ChEBI: An organic chloride salt having tetrazolium blue(1+) as the counterion.

Properties of Tetrazolium Blue Chloride

Melting point:	255 °C (dec.)(lit.)
Density	1.9137 (rough estimate)
refractive index	1.6000 (estimate)
storage temp.	room temp
solubility	Soluble in water;freely soluble ethanol, methanol, chloroform; insoluble in acetone, ether, ethyl acetate
form	crystals or powder
color	Lemon yellow
Odor	Odorless
Water Solubility	Soluble in hot water (5 mg/ml), methanol (50 mg/ml), ethanol, and chloroform. Insoluble in acetone.
λmax	253 nm
Merck	14,9244
BRN	3894077
Stability:	Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
Biological Applications	Cellular response evaluation assays; microbial growth assays; tannins assays; anti-cancer agents; diagnostic test strips; detecting lactate dehydrogenase (LDH) isoenzymes,gamma-hydroxybutyric acid (GHB); measuring ATP,numb
CAS DataBase Reference	1871-22-3(CAS DataBase Reference)
EPA Substance Registry System	2H-Tetrazolium, 2,2'-(3,3'-dimethoxy[1,1'-biphenyl]-4,4'-diyl)bis[3,5-diphenyl-, dichloride (1871-22-3)

Safety information for Tetrazolium Blue Chloride

Signal word	Danger
Pictogram(s)	Health Hazard GHS08
GHS Hazard Statements	H350:Carcinogenicity
Precautionary Statement Codes	P201:Obtain special instructions before use. P202:Do not handle until all safety precautions have been read and understood. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. P405:Store locked up. P501:Dispose of contents/container to..…