Tetrabutyl orthosilicate
Synonym(s):Tetrabutoxysilane
- CAS NO.:4766-57-8
- Empirical Formula: C16H36O4Si
- Molecular Weight: 320.54
- MDL number: MFCD00009432
- EINECS: 225-305-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02

What is Tetrabutyl orthosilicate?
Chemical properties
Colorless transparent liquid
The Uses of Tetrabutyl orthosilicate
It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields and also in the alkylation and alkoxylation of silane.
Properties of Tetrabutyl orthosilicate
Melting point: | -80 °C |
Boiling point: | 275 °C (lit.) |
Density | 0.899 g/mL at 25 °C (lit.) |
vapor density | >1 (vs air) |
refractive index | n |
Flash point: | 174 °F |
storage temp. | Sealed in dry,Room Temperature |
form | liquid |
color | colorless |
Specific Gravity | 0.9 |
Water Solubility | reacts |
Sensitive | Moisture Sensitive |
Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
BRN | 1709274 |
CAS DataBase Reference | 4766-57-8(CAS DataBase Reference) |
NIST Chemistry Reference | Tetrabutyl silicate(4766-57-8) |
EPA Substance Registry System | Silicic acid (H4SiO4), tetrabutyl ester (4766-57-8) |
Safety information for Tetrabutyl orthosilicate
Signal word | Warning |
Pictogram(s) |
![]() Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P321:Specific treatment (see … on this label). P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Tetrabutyl orthosilicate
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