Testosterone isocaproate

Synonym(s):4-Androsten-17β-ol-3-one 17-(4-methylpentanoate);Testosterone 4-methylvalerate

CAS NO.：15262-86-9
Empirical Formula: C25H38O3
Molecular Weight: 386.57
MDL number: MFCD00133848
EINECS: 239-307-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-11 20:10:50

What is Testosterone isocaproate?

Description

Testosterone isocaproate is a testosterone ester with improved bioavailability and metabolic half life compared to the endogenous hormone.It used to testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis.

Chemical properties

White or almost white powder.

The Uses of Testosterone isocaproate

Testosterone Isocaproate is used in the treatment of male hypogonadism (a condition in which the body does not produce enough testosterone).

Definition

ChEBI: Testosterone isocaproate is a steroid ester.

Mode of action

Testosterone Isocaproate is similar to the natural male hormone, testosterone. Testosterone binds to the androgen receptor (AR), and the ligand-receptor complex translocates to the nucleus and binds to androgen response elements (AREs) on chromosomal DNA, thereby modulating transcription of a set of androgen-responsive genes. Testosterone can also be converted to estrogen and has a similar regulatory action on genes containing estrogen response elements (EREs).

Properties of Testosterone isocaproate

Melting point:	79-80 °C
Boiling point:	487.6±45.0 °C(Predicted)
Density	1.07±0.1 g/cm3(Predicted)
solubility	Practically insoluble in water, very soluble in acetone and in methylene chloride, freely soluble in fatty oils.
form	neat
InChI	InChI=1/C25H38O3/c1-16(2)5-10-23(27)28-22-9-8-20-19-7-6-17-15-18(26)11-13-24(17,3)21(19)12-14-25(20,22)4/h15-16,19-22H,5-14H2,1-4H3/t19-,20-,21-,22-,24-,25-/s3
CAS DataBase Reference	15262-86-9(CAS DataBase Reference)

Safety information for Testosterone isocaproate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H351:Carcinogenicity H361:Reproductive toxicity H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Testosterone isocaproate

InChIKey	PPYHLSBUTAPNGT-BKWLFHPQSA-N
SMILES	[C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCC(C)C \|&1:0,10,12,16,18,21,r\|