Androstenedione
- CAS NO.:63-05-8
- Empirical Formula: C19H26O2
- Molecular Weight: 286.41
- MDL number: MFCD00003615
- EINECS: 200-554-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-21 13:23:50
What is Androstenedione?
Description
Androstenedione (CRM) (Item No. ISO60161) is a certified reference material categorized as an anabolic androgenic steroid. Androstenedione is a precursor of testosterone (Item Nos. ISO60154 | ISO00154 | 15645) and estrone . Androstenedione is regulated as a Schedule III compound in the United States. Androstenedione (CRM) (Item No. ISO60161) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.
Chemical properties
White to Off-White Solid
The Uses of Androstenedione
Testosterone precursor and metabolite with androgenic activity. Controlled substance (anabolic sterid)
Definition
ChEBI: A 3-oxo Delta4-steroid that is androst-4-ene substituted by oxo groups at positions 3 and 17. It is a steroid hormone synthesized in the adrenal glands and gonads.
Safety Profile
An experimental teratogen. Otherexperimental reproductive effects. Questionablecarcinogen with experimental tumorigenic data. Whenheated to decomposition it emits acrid smoke andirritating fumes.
Purification Methods
Crystallise the dione from hexane. It is soluble in *C6H6, CHCl3 and EtOH. It has max at 239nm. It is a precursor of estrone or testosterone and has androgenic activity. [Ruzicka & Wettstein Helv Chim Acta 18 980 1935, Beilstein 7 III 3636, 7 IV 2381.]
Properties of Androstenedione
Melting point: | 170-171 °C(lit.) |
Boiling point: | 368.77°C (rough estimate) |
alpha | D30 +199° (in chloroform) |
Density | 1.0655 (rough estimate) |
refractive index | 1.4709 (estimate) |
Flash point: | 2℃ |
storage temp. | Controlled Substance, -20°C Freezer |
solubility | Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Sparingly) |
form | Solid |
color | Dimorphous: Needles from acetone, or crystalsfrom hexane |
Water Solubility | 57.28mg/L(25 ºC) |
Merck | 13,643 |
CAS DataBase Reference | 63-05-8(CAS DataBase Reference) |
NIST Chemistry Reference | Androst-4-ene-3,17-dione(63-05-8) |
EPA Substance Registry System | 4-Androstenedione (63-05-8) |
Safety information for Androstenedione
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H225:Flammable liquids H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Androstenedione
InChIKey | AEMFNILZOJDQLW-QAGGRKNESA-N |
Abamectin manufacturer
Orgamine Chemicals(I) Pvt Ltd
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