Testosterone decanoate

Synonym(s):17β-Hydroxy-4-androsten-3-one 17-decanoate;4-Androsten-17β-ol-3-one 17-caprate

CAS NO.：5721-91-5
Empirical Formula: C29H46O3
Molecular Weight: 442.67
MDL number: MFCD00133847
EINECS: 227-226-4
SAFETY DATA SHEET (SDS)
Update Date: 2025-03-20 19:16:41

What is Testosterone decanoate?

Description

Testosterone Decanoate is one of the many esterified forms of testosterone and is a long form of the testosterone as it offers a long half life after administration. This is actually an androgen and anabolic steroid and a testosterone ester, a potent long acting injectable male synthetic hormone. Testosterone Decanoate is second longest acting form of testosterone after Testosterone Undecanoate. As with any other form of testosterone, the only difference between them is in the half life (the release time of the hormone after it got administered).

Chemical properties

White or almost white powder.

The Uses of Testosterone decanoate

Testosterone decanoate is an androgen that mainly used by men to maintain the second sexual sign, sexual desire and male psychology. It is an steroid indicated for testosterone replacement therapy in sterilization, missing testicle, hypopituitarism, and osteoporosis.

Definition

ChEBI: Testosterone decanoate is a steroid ester.

Mechanism of action

Testosterone binds to the androgen receptor (AR), and the ligand-receptor complex translocates to the nucleus and binds to androgen response elements (AREs) on chromosomal DNA, thereby modulating transcription of a set of androgen-responsive genes. Testosterone can also be converted to estrogen and has a similar regulatory action on genes containing estrogen response elements (EREs).

Properties of Testosterone decanoate

Melting point:	38 °C
Boiling point:	539.2±50.0 °C(Predicted)
Density	1.04±0.1 g/cm3(Predicted)
solubility	Practically insoluble in water, very soluble in acetone, in methylene chloride and in anhydrous ethanol, freely soluble in fatty oils.
form	neat
CAS DataBase Reference	5721-91-5(CAS DataBase Reference)

Safety information for Testosterone decanoate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H351:Carcinogenicity H361:Reproductive toxicity H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Testosterone decanoate

InChIKey	LBERVHLCXUMDOT-MPZZESAYSA-N
SMILES	[C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCCCCCCCC \|&1:0,10,12,16,18,21,r\|