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HomeProduct name listSUFENTANIL CITRATE

SUFENTANIL CITRATE

Synonym(s):N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide citrate;R-33800;Sufentanyl citrate

  • CAS NO.:60561-17-3
  • Empirical Formula: C28H38N2O9S
  • Molecular Weight: 578.68
  • MDL number: MFCD00072116
  • EINECS: 262-295-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 09:03:07
SUFENTANIL CITRATE Structural

What is SUFENTANIL CITRATE?

Chemical properties

Crystalline Solid

The Uses of SUFENTANIL CITRATE

Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)

Definition

ChEBI: Sufentanil citrate is an anilide.

brand name

Sufenta (Akorn).

General Description

Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.

Clinical Use

Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.

Veterinary Drugs and Treatments

An opioid analgesic, sufentanil may be useful as an anesthesia adjunct or as an epidural analgesic. In humans, it has been used as the primary anesthetic in intubated patients with assisted ventilation, and as a post-operative analgesic.

Properties of SUFENTANIL CITRATE

Melting point: 96.60C
Flash point: 9℃
storage temp.  -20°C Freezer
solubility  H2O: soluble1mg/mL, clear
form  powder
color  white to beige
Stability: Hygroscopic

Safety information for SUFENTANIL CITRATE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P262:Do not get in eyes, on skin, or on clothing.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for SUFENTANIL CITRATE

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