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Sophoridine

Sophoridine Structural

What is Sophoridine?

Description

One of a number of minor alkaloids isolated from Leontice albertii Rgl., this base crystallizes from petroleum ether as colourless prisms. It is dextrorotatory having a specific rotation of [α]D + 59.3° (c 1.3, EtOH) and yields a crystalline methiodide, m.p. 249°C. The structure has been assigned on the basis of chemical analysis and spectroscopic determinations.

The Uses of Sophoridine

(+)-Sophoridine acts as an anti-inflammatory agent in vitro and in vivo. Anticancer agent, with a promising anti-tumor effect and lower toxicity.

References

Kamalitdinov, Iskandarov, Yunusov, Khim. Prir. Soedin., 3, 352 (1967)
Kamalitdinov, Iskandarov, Yunusov, ibid, 5,409 (1969)

Properties of Sophoridine

Melting point: 108-9°C
Boiling point: 396.7±31.0 °C(Predicted)
Density  1.16±0.1 g/cm3(Predicted)
solubility  Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
pka 9.47±0.20(Predicted)
color  Pale Yellow
CAS DataBase Reference 83148-91-8

Safety information for Sophoridine

Computed Descriptors for Sophoridine

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