SOLANIDINE

Synonym(s):(3β)-Solanid-5-en-3-ol;Solatubine

CAS NO.：80-78-4
Empirical Formula: C27H43NO
Molecular Weight: 397.64
MDL number: MFCD00056839
EINECS: 201-309-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is SOLANIDINE?

The Uses of SOLANIDINE

Soladine has been shown to display mutagenic properties in the liver, and is stored in the body for prolonged periods of time.

Definition

ChEBI: Solanidine is a steroid alkaloid fundamental parent, a 3beta-hydroxy-Delta(5)-steroid and a solanid-5-en-3-ol. It has a role as a plant metabolite and a toxin. It is a conjugate base of a solanidine(1+).

Purification Methods

Solanidine crystallises from CHCl3/MeOH, aqueous EtOH or aqueous MeOH as needles. TLC on Al2O3 plates using CH2Cl2/MeOH (98:2) gives a spot at RF 0.47. The hydrochloride crystallises from aqueous EtOH with m 345o(dec). The acetate crystallises from EtOH with m 208o. [Schreiber & Roensch Tetrahedron 21 6451965, Kessar et al. Tetrahedron 27 2153 1971, Reichestein & Reich Ann Rev Biochem 15 155 1946, Beilstein 21 III/IV 1398, 27 III/IV 2000.]

Properties of SOLANIDINE

Melting point:	212-214°C
alpha	D21 -29° (c = 0.5 in chloroform)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly, Heated)
form	Solid
color	White to Off-White

Safety information for SOLANIDINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H302:Acute toxicity,oral H413:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P202:Do not handle until all safety precautions have been read and understood. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P308+P313:IF exposed or concerned: Get medical advice/attention.