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HomeProduct name listSodium diethyldithiocarbamate trihydrate

Sodium diethyldithiocarbamate trihydrate

Synonym(s):Cupral;Diethyldithiocarbamic acid sodium salt;Sodium diethyldithiocarbamate trihydrate

  • CAS NO.:20624-25-3
  • Empirical Formula: C5H14NNaOS2
  • Molecular Weight: 191.28
  • MDL number: MFCD00150617
  • EINECS: 677-810-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-30 18:52:02
Sodium diethyldithiocarbamate trihydrate Structural

What is Sodium diethyldithiocarbamate trihydrate?

Chemical properties

white to light yellow crystals

The Uses of Sodium diethyldithiocarbamate trihydrate

Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. Sodium diethyldithiocarbamate trihydrate is a copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

The Uses of Sodium diethyldithiocarbamate trihydrate

A possible nuclear factor kappa B inhibitor.

The Uses of Sodium diethyldithiocarbamate trihydrate

Sodium diethyldithiocarbamate trihydrate is a spin trapping reagent used in conjunction with ferrous ion to detect nitric oxide in brain, kidney, liver and other tissues. It is used as sensitive reagent for the determination of copper, rubber vulcanization accelerator and finds application in the determination of other metals such as zinc, cobalt, platinum and palladium. Furthermore, it is an inhibitor of superoxide dismutase, ascorbate oxidase and other enzymes as well as inhibits the induction of macrophage nitric oxide synthase.

What are the applications of Application

Diethyldithiocarbamic acid sodium salt trihydrate is a Nitric oxide (NO) spin-trapping reagent

General Description

Sodium diethyldithiocarbamate trihydrate may be used:

  • To synthesize cis-dichlorobis(N,N-diethyldithiocarbamato) tin(IV) by reacting with tin(II) chloride.
  • As an alternative to xanthates to generate carbamoyl radical precursors.
  • To synthesize a soluble precursor polymer for poly(thienylene vinylene).
  • To synthesize dichlorotetrakis(dimethyl sulfoxide)ruthenium (II), which can be a precursor to prepare other ruthenium complexes.[17}

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Purification Methods

Recrystallise it from water. [Beilstein 4 III 224, 4 IV 390.]

Properties of Sodium diethyldithiocarbamate trihydrate

Melting point: 95-98.5 °C(lit.)
Density  1.100
vapor density  5.9 (vs air)
storage temp.  room temp
solubility  H2O: passes test
form  Crystals or Powder
color  White to off-white
Odor Odorless
PH 7 (20g/l, H2O, 20℃)
PH Range 11.6
Water Solubility  FREELY SOLUBLE
Sensitive  Hygroscopic
Merck  14,3378
BRN  3920507
Stability: Stable. Incompatible with strong oxidizing agents. Hygroscopic.
CAS DataBase Reference 20624-25-3(CAS DataBase Reference)

Safety information for Sodium diethyldithiocarbamate trihydrate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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