Sodium diethyldithiocarbamate trihydrate
Synonym(s):Cupral;Diethyldithiocarbamic acid sodium salt;Sodium diethyldithiocarbamate trihydrate
- CAS NO.:20624-25-3
- Empirical Formula: C5H14NNaOS2
- Molecular Weight: 191.28
- MDL number: MFCD00150617
- EINECS: 677-810-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-30 18:52:02
What is Sodium diethyldithiocarbamate trihydrate?
Chemical properties
white to light yellow crystals
The Uses of Sodium diethyldithiocarbamate trihydrate
Spin trap used in conjunction with Fe2+ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO2 has been reported. Sodium diethyldithiocarbamate trihydrate is a copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.
The Uses of Sodium diethyldithiocarbamate trihydrate
A possible nuclear factor kappa B inhibitor.
The Uses of Sodium diethyldithiocarbamate trihydrate
Sodium diethyldithiocarbamate trihydrate is a spin trapping reagent used in conjunction with ferrous ion to detect nitric oxide in brain, kidney, liver and other tissues. It is used as sensitive reagent for the determination of copper, rubber vulcanization accelerator and finds application in the determination of other metals such as zinc, cobalt, platinum and palladium. Furthermore, it is an inhibitor of superoxide dismutase, ascorbate oxidase and other enzymes as well as inhibits the induction of macrophage nitric oxide synthase.
What are the applications of Application
Diethyldithiocarbamic acid sodium salt trihydrate is a Nitric oxide (NO) spin-trapping reagent
General Description
Sodium diethyldithiocarbamate trihydrate may be used:
- To synthesize cis-dichlorobis(N,N-diethyldithiocarbamato) tin(IV) by reacting with tin(II) chloride.
- As an alternative to xanthates to generate carbamoyl radical precursors.
- To synthesize a soluble precursor polymer for poly(thienylene vinylene).
- To synthesize dichlorotetrakis(dimethyl sulfoxide)ruthenium (II), which can be a precursor to prepare other ruthenium complexes.[17}
Biochem/physiol Actions
Inhibits induction of macrophage nitric oxide synthase.
Purification Methods
Recrystallise it from water. [Beilstein 4 III 224, 4 IV 390.]
Properties of Sodium diethyldithiocarbamate trihydrate
Melting point: | 95-98.5 °C(lit.) |
Density | 1.100 |
vapor density | 5.9 (vs air) |
storage temp. | room temp |
solubility | H2O: passes test |
form | Crystals or Powder |
color | White to off-white |
Odor | Odorless |
PH | 7 (20g/l, H2O, 20℃) |
PH Range | 11.6 |
Water Solubility | FREELY SOLUBLE |
Sensitive | Hygroscopic |
Merck | 14,3378 |
BRN | 3920507 |
Stability: | Stable. Incompatible with strong oxidizing agents. Hygroscopic. |
CAS DataBase Reference | 20624-25-3(CAS DataBase Reference) |
Safety information for Sodium diethyldithiocarbamate trihydrate
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Sodium diethyldithiocarbamate trihydrate
Abamectin manufacturer
East Coast Organics
DeFINE CHEMICALS
Vijaya Pharma And Life Science
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