Sodium dehydroacetate

Synonym(s):2-Acetyl-5-hydroxy-3-oxo-4-hexenoic acid δ-lactone sodium salt;3-(1-Hydroxyethylidene)-6-methyl-2H-pyran-2,4(3H)-dione sodium salt;Dehydroacetic acid sodium salt

CAS NO.：4418-26-2
Empirical Formula: C8H7NaO4
Molecular Weight: 190.13
MDL number: MFCD00040583
EINECS: 224-580-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 11:14:03

What is Sodium dehydroacetate ?

Description

Sodium dehydroacetate is the sodium salt of dehydroacetate. It is mainly used as a new generation food preservative and food additive, being used extensively in sauce, fruit, bread, cake, moon cake, margarine and beverage. Sodium dehydroacetate (DHA-S) has a wide spectrum of antimicrobial activity that accounts for its use in cosmetic products as a preservative and antimicrobial agent. It is effective in the treatment of both bacteria and fungi. It is also a kind of anticoagulant agent through depleting the blood level of vitamin K.

Chemical properties

White to yellowish powder

The Uses of Sodium dehydroacetate

sodium dehydroacetate is a preservative against bacteria and fungi that is used at concentration levels of 1.0 percent or less. It is useful in combination with parabens. It may cause skin irritation.

The Uses of Sodium dehydroacetate

Dehydroacetic acid sodium salt (DHS-Na) is used in the food industry as preservative for fruits, vegetables, fruit juice, honey, beer, milk, protein and fat products; in human and veterinary medicine as bactericide and fungicide. Product Data Sheet

The Uses of Sodium dehydroacetate

Geogard(R) 111S preservative is based on dehydroacetic acid (DHA), the sodium salt form (NaDHA) and therefore are recognized by major cosmetic, toiletry and fragrance regulatory authorities worldwide for use in cosmetic and personal care products.

General Description

White powder. Used as a fungicide, plasticizer, toothpaste, preservative in food.

Air & Water Reactions

Water soluble.

Reactivity Profile

Sodium dehydroacetate reacts with acids. May react viogrously with strong oxidizing acids.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. An eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O

References

Forester, John. "Preservative solutions containing sodium dehydroacetate with or without sodium borate decahydrate and/or disodium edetate." US, US4248634. 1981.
Sakaguchi, Yuka, et al. "Anticoagulant effect of sodium dehydroacetate (DHA-S) in rats." Journal of Applied Toxicology 28.4(2008):524-529.
Ye, Yinzhi. "Use of Sodium Dehydroacetate in Food." China Food Additives (2002).

Properties of Sodium dehydroacetate

Melting point:	~295 °C (dec.)
Density	1.499[at 20℃]
vapor pressure	0Pa at 25℃
storage temp.	Store below +30°C.
solubility	330g/l
form	Powder
pka	5.36[at 20 ℃]
color	White to yellow
PH	8.8-9.3 (100g/l, H2O, 20℃)
Water Solubility	Soluble in water, propylene glycol and methanol. Insoluble in acetone and benzene.
BRN	4893653
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	4418-26-2(CAS DataBase Reference)
EPA Substance Registry System	3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium (4418-26-2)

Safety information for Sodium dehydroacetate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..…