Lithium acetate

Description

Lithium acetate (CH₃COOLi) is a salt of lithium and acetic acid.

Chemical properties

solid

The Uses of Lithium acetate

Lithium acetate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It has a lower electrical conductivity and can be run at higher speeds than can gels made from TAE buffer (5-30V/cm as compared to 5 - 10 V / cm). Lithium boric acid or sodium boric acid are usually preferable to lithium acetate or TAE when analyzing smaller fragments of DNA (less than 500 bp) due to the higher resolution of borate-based buffers in this size range as compared to acetate buffers.
Lithium acetate is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is believed that the beneficial effect of LiAc is caused by its chaotropic effect denaturing both DNA, RNA and proteins.

The Uses of Lithium acetate

Lithium acetate hydrate is used in the laboratory as buffer for gel electrophoresis of DNA and RNA. It is also used to permeabilize the cell wall of yeast for use in DNA transformation. It is a metal acetate for proteomics research.

The Uses of Lithium acetate

Lithium acetate (LiOAc) is a lithium source and a doping salt which can be used in the preparation of plasticized polymer electrolytes for lithium-ion batteries. It can be used as a monovalent cation, which improves the transformation efficiency of Saccharomyces cerevisiae.

What are the applications of Application

Lithium acetate is a metal acetate for proteomics research

Definition

ChEBI: An acetate salt comprising equal numbers of acetate and lithium ions.

Flammability and Explosibility

Non flammable

Safety Profile

Poison by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALUMINUM and LITHIUM COMPOUNDS.