SNAP
Synonym(s):(±)-S-Nitroso-N-acetylpenicillamine - CAS 79032-48-7 - Calbiochem;SNAP
- CAS NO.：79032-48-7
- Empirical Formula: C7H12N2O4S
- Molecular Weight: 220.25
- MDL number: MFCD00153852
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is SNAP?
Chemical properties
Green Crystalline Solid
The Uses of SNAP
The D-isomer of SNAP. Serves as an NO donor
The Uses of SNAP
The D-isomer of SNAP. Serves as an NO donor.
What are the applications of Application
(±)-S-Nitroso-N-acetylpenicillamine is a cysteine protease inhibitor and spontaneous NO donor in physiological conditions
Definition
ChEBI: A nitroso compound that is N-acetyl-D-penicillamine in which the sulfanyl hydrogen is replaced by a nitroso group.
General Description
Nitric oxide donor that begins to evolve nitric oxide immediately upon solubilization in aqueous buffers (t1/2 = 10 h). Mimics the actions of nitric oxide, including the relaxation of isolated bovine coronary artery rings (EC50 = 130 nM). Markedly activates soluble guanylate cyclase. Also reported to cause the reversible inactivation of protein kinase C activity. Induces apoptosis in mouse thymocytes. Note: 1 set = 4 x 5 mg.
Biological Activity
A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t ?of 37h.
Biochem/physiol Actions
EC50 = 130 nM in relaxation of isolated bovine coronary artery rings
storage
Store at -20°C
Properties of SNAP
| Density | 1.36±0.1 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: ≥2 mg/mL |
| form | powder |
| pka | 3.06±0.10(Predicted) |
| color | green |
Safety information for SNAP
Computed Descriptors for SNAP
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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