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HomeProduct name listSB 222200

SB 222200

Synonym(s):(S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide

SB 222200 Structural

What is SB 222200?

The Uses of SB 222200

3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2).

What are the applications of Application

SB 222200 is a potent, selective non-peptide NK3 antagonist

Definition

ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.

Biological Activity

Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo .

storage

Store at RT

Properties of SB 222200

Melting point: 154℃
Boiling point: 553.5±50.0 °C(Predicted)
Density  1.142
storage temp.  Sealed in dry,2-8°C
solubility  DMSO: ~28 mg/mL, soluble
form  solid
pka 12.88±0.46(Predicted)
color  light yellow

Safety information for SB 222200

Computed Descriptors for SB 222200

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