SB 222200
Synonym(s):(S)-3-Methyl-2-phenyl-N-(1-phenylpropyl)-4-quinolinecarboxamide
- CAS NO.：174635-69-9
- Empirical Formula: C26H24N2O
- Molecular Weight: 380.48
- MDL number: MFCD00944072
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is SB 222200?
The Uses of SB 222200
3-Methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a chemical agent used in the preparation of acylpiperazinyl-pyrazoles as antagonists to the NK3 receptor as antipsychotics (1,2).
What are the applications of Application
SB 222200 is a potent, selective non-peptide NK3 antagonist
Definition
ChEBI: 3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.
Biological Activity
Potent and selective non-peptide NK 3 receptor antagonist. K i values are 4.4, >100,000 and 250 nM for human NK 3 , NK 1 and NK 2 receptors respectively. Brain penetrant and active in vivo .
storage
Store at RT
Properties of SB 222200
| Melting point: | 154℃ |
| Boiling point: | 553.5±50.0 °C(Predicted) |
| Density | 1.142 |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ~28 mg/mL, soluble |
| form | solid |
| pka | 12.88±0.46(Predicted) |
| color | light yellow |
Safety information for SB 222200
Computed Descriptors for SB 222200
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![SB 222200, [3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure7/GIF/CB6438432.gif)
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