4-Aminodiphenylamine

Synonym(s):4-Aminodiphenylamine;Diphenyl black, N-Phenyl-p-phenylenediamine;Variamine Blue RT Base

CAS NO.：101-54-2
Empirical Formula: C12H12N2
Molecular Weight: 184.24
MDL number: MFCD00007850
EINECS: 202-951-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 16:48:35

What is 4-Aminodiphenylamine?

Description

p-Aminodiphenylamine hydrochloride was formerly used as a hair dye. Sensitization, when deteeted by patch testing, is relatively low in hairdressers.

Chemical properties

Dark grey flake

The Uses of 4-Aminodiphenylamine

4-Aminodiphenylamine is used as an oxidation dye color in hair dyes. It is also promoted as an efficient reagent for oxidase enzymes, including glucose, lactate, xanthine, and lysine oxidases.

The Uses of 4-Aminodiphenylamine

Dye intermediate, pharmaceuticals, photographic chemicals.

The Uses of 4-Aminodiphenylamine

p-Anilinoaniline is an antioxidant that has shown to cause a reduction of NOx emissions from soybean biodiesel powered DI diesel engines but has increased CO and HC emissions. It is also used to produce dyes, pharmaceuticals, and photographic chemicals and frmerly used as a hair dye.

Definition

ChEBI: An aromatic amine that is the 4-amino derivative of diphenylamine.

General Description

Odorless purple-black solid or flake or dark purple chips.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

4-Aminodiphenylamine is incompatible with strong oxidizers. 4-Aminodiphenylamine is also incompatible with strong acids. 4-Aminodiphenylamine may react with plastics.

Fire Hazard

4-Aminodiphenylamine is combustible.

Contact allergens

This substance was formerly used as a hair dye. Sensitization, when detected by patch testing, is relatively low in hairdressers.

Purification Methods

It crystallises from EtOH with m 66o, and from ligroin with m 75o. It can be distilled at high vacuum. [Beilstein 13 IV 113.]

Properties of 4-Aminodiphenylamine

Melting point:	69 °C
Boiling point:	354 °C
Density	1.09
vapor pressure	1 hPa
refractive index	1.6266 (estimate)
Flash point:	193°C
storage temp.	Store below +30°C.
solubility	ethanol: soluble10mg/mL, clear, very dark red (Violet to brown to black solution)
form	Liquid
pka	5.20±0.10(Predicted)
Colour Index	37240
color	Clear
PH	8.9 (0.5g/l, H2O, 20℃)
Water Solubility	Soluble in water at 20°C 0.6g/L. Soluble in (10 mg/mL) ethanol.
BRN	908935
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents, strong acids, plastics.
CAS DataBase Reference	101-54-2(CAS DataBase Reference)
NIST Chemistry Reference	1,4-Benzenediamine, N-phenyl-(101-54-2)
EPA Substance Registry System	p-Aminodiphenylamine (101-54-2)

Safety information for 4-Aminodiphenylamine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.