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HomeProduct name listSARPAGINE

SARPAGINE

  • CAS NO.:482-68-8
  • Empirical Formula: C19H22N2O2
  • Molecular Weight: 310.39
  • MDL number: MFCD29078461
  • EINECS: 207-583-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
SARPAGINE Structural

What is SARPAGINE?

Description

This base has been isolated from Rauwolfia serpentina and is an isomer of Ajmalinine (q.v.). Pharmacologically it has between three and four times the effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body weight. The toxicity is low.

Definition

ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17.

References

Bodendorf, Eder., Naturwis<., 40, 342 (1953)

Properties of SARPAGINE

Melting point: 320°C
Boiling point: 450.55°C (rough estimate)
alpha  D20 +54° (c = 0.5 in pyridine)
Density  1.1396 (rough estimate)
refractive index  1.5600 (estimate)
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder
pka 10.24±0.40(Predicted)

Safety information for SARPAGINE

Computed Descriptors for SARPAGINE

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