hydroxygenkwanin

Synonym(s):3′,4′,5-Trihydroxy 7-methoxyflavone;3′-Hydroxygenkwanin;7-O-Methylluteolin

CAS NO.：20243-59-8
Empirical Formula: C16H12O6
Molecular Weight: 300.26
MDL number: MFCD11046350
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-05 08:26:49

What is hydroxygenkwanin?

Chemical properties

Yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from coriander flower.

The Uses of hydroxygenkwanin

Hydroxyflorin has antitussive, expectorant and asthmatic effects.

Definition

ChEBI: Luteolin 7-methyl ether is a member of flavonoids and an ether. It is a conjugate acid of a luteolin-5-olate 7-methyl ether.

Biological Activity

Hydroxygenkwanin (7-O-Methylluteolin) is a natural flavonoid that is one of the main components of Clove Daphne. It has antioxidant, antiglioma and anticancer effects.

in vitro

Hydroxygenkwanin (7-O-Methylluteolin) inhibits C6 glioma cell proliferation in a dose dependent manner.
It induces the cell cycle arrest by flow cytometry and inhibits colony formation ability and cell movement. Hydroxygenkwanin induces cell cycle arrest through p21 activation and causes intrinsic cell apoptosis pathway.

Properties of hydroxygenkwanin

Melting point:	258-260 °C
Boiling point:	602.7±55.0 °C(Predicted)
Density	1.512±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMF: 1 mg/ml; DMSO: 2 mg/ml
form	A solid
pka	6.33±0.40(Predicted)
color	Light yellow to green yellow