S(-)-RACLOPRIDE L-TARTRATE
Synonym(s):(S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem;Dopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
- CAS NO.：84225-95-6
- Empirical Formula: C15H20Cl2N2O3
- Molecular Weight: 347.24
- MDL number: MFCD02179386
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-20 16:43:00
What is S(-)-RACLOPRIDE L-TARTRATE?
Description
Raclopride is a selective dopamine D2/D3 receptor antagonist with Ki values of 1.8, 3.5, 2,400, and 18,000 nM for D2, D3, D4, and D1 receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.
Chemical properties
Yellowish solid
The Uses of S(-)-RACLOPRIDE L-TARTRATE
A labelled dopamine receptor
The Uses of S(-)-RACLOPRIDE L-TARTRATE
neuroleptic;selective dopamine D1/D2 receptors antagonist
The Uses of S(-)-RACLOPRIDE L-TARTRATE
Raclopride is a potent D2DR/D3DR antagonist.
What are the applications of Application
Raclopride is a potent D2DR/D3DR antagonist
Definition
ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.
Biological Activity
Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .
storage
Store at -20°C
Properties of S(-)-RACLOPRIDE L-TARTRATE
| Melting point: | 52.0 to 56.0 °C |
| Boiling point: | 420.3±45.0 °C(Predicted) |
| Density | 1.288±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | H2O: 89 mg/mL |
| form | solid |
| pka | 5.93±0.50(Predicted) |
| color | white |
Safety information for S(-)-RACLOPRIDE L-TARTRATE
Computed Descriptors for S(-)-RACLOPRIDE L-TARTRATE
New Products
Tubulysin F Tubulysin H (2S,4R)-4-amino-2-methyl-5-phenylpentanoic acid hydrochloride Tubulysin E Diethyl Aluminium Cyanide (1.0 M in Toluene) 4,4-DIFLUOROCYCLOHEXANAMINE 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 4,4-DIFLUOROPIPERIDINE CYCLOBUTYLAMINE HYDROCHLORIDE Isoxazole, 3-[[[5-(difluoromethoxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]thio]-4,5-dihydro-5,5-dimethyl- Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate Calcium Sodium Phosphosilicate IH Imeglimin Hydrochloride IH 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Lubiprostone Latanoprostene Bunod Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrileRelated products of tetrahydrofuran
![(S)-RACLOPRIDE, [METHOXY-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB3175011.gif)
You may like
-
Raclopride CAS 84225-95-6View Details
84225-95-6 -
Raclopride 95% CAS 84225-95-6View Details
84225-95-6 -
(S)-(-)-Raclopride CAS 84225-95-6View Details
84225-95-6 -
(R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonateView Details
2416850-45-6 -
methyl 3-fluoro-4- thiomorpholino phenylcarbamateView Details
2760359-22-4 -
4,6-dichloro-2-propylthiopyrimidine-5-amine 145783-15-9 98%View Details
145783-15-9 -
Valacyclovir Hydrochloride IH 98%View Details
124832-27-5 -
2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 98%View Details
142569-70-8