S(-)-RACLOPRIDE L-TARTRATE

Description

Raclopride is a selective dopamine D₂/D₃ receptor antagonist with K_i values of 1.8, 3.5, 2,400, and 18,000 nM for D₂, D₃, D₄, and D₁ receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.

Chemical properties

Yellowish solid

The Uses of S(-)-RACLOPRIDE L-TARTRATE

A labelled dopamine receptor

The Uses of S(-)-RACLOPRIDE L-TARTRATE

neuroleptic;selective dopamine D1/D2 receptors antagonist

The Uses of S(-)-RACLOPRIDE L-TARTRATE

Raclopride is a potent D2DR/D3DR antagonist.

What are the applications of Application

Raclopride is a potent D2DR/D3DR antagonist

Definition

ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.

Biological Activity

Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .

Storage

Store at -20°C