S(-)-RACLOPRIDE L-TARTRATE
Synonym(s):(S)-(-)-Raclopride - CAS 84225-95-6 - Calbiochem;Dopamine Receptor D2 Antagonist, (S)-Raclopride, Raclopride
- CAS NO.：84225-95-6
- Empirical Formula: C15H20Cl2N2O3
- Molecular Weight: 347.24
- MDL number: MFCD02179386
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is S(-)-RACLOPRIDE L-TARTRATE?
Description
Raclopride is a selective dopamine D2/D3 receptor antagonist with Ki values of 1.8, 3.5, 2,400, and 18,000 nM for D2, D3, D4, and D1 receptors, respectively. It passes the blood brain barrier and can be used in in vivo binding and autoradiography studies of the dopamine system under normal and pathological conditions such as Huntington’s disease.
Chemical properties
Yellowish solid
The Uses of S(-)-RACLOPRIDE L-TARTRATE
A labelled dopamine receptor
The Uses of S(-)-RACLOPRIDE L-TARTRATE
neuroleptic;selective dopamine D1/D2 receptors antagonist
The Uses of S(-)-RACLOPRIDE L-TARTRATE
Raclopride is a potent D2DR/D3DR antagonist.
What are the applications of Application
Raclopride is a potent D2DR/D3DR antagonist
Definition
ChEBI: 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide is a member of salicylamides.
Biological Activity
Selective and potent dopamine D 2 /D 3 receptor antagonist (K i values are 1.8, 3.5, 2400 and 18000 nM for D 2 , D 3 , D 4 and D 1 receptors respectively). Centrally active following systemic administration in vivo .
storage
Store at -20°C
Properties of S(-)-RACLOPRIDE L-TARTRATE
| Melting point: | 52.0 to 56.0 °C |
| Boiling point: | 420.3±45.0 °C(Predicted) |
| Density | 1.288±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,2-8°C |
| solubility | H2O: 89 mg/mL |
| form | solid |
| pka | 5.93±0.50(Predicted) |
| color | white |
Safety information for S(-)-RACLOPRIDE L-TARTRATE
Computed Descriptors for S(-)-RACLOPRIDE L-TARTRATE
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![(S)-RACLOPRIDE, [METHOXY-3H]](https://img.chemicalbook.in/StructureFile/ChemBookStructure2/GIF/CB3175011.gif)
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