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HomeProduct name listS-(-)-LISURIDE

S-(-)-LISURIDE

  • CAS NO.:18016-80-3
  • Empirical Formula: C20H26N4O
  • Molecular Weight: 338.45
  • MDL number: MFCD00274053
  • EINECS: 241-925-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-04 17:34:35
S-(-)-LISURIDE Structural

What is S-(-)-LISURIDE?

The Uses of S-(-)-LISURIDE

A dopamine and serotonin receptor partial agonist with high affinity for the dopamine D2, D3 and D4 receptors, as well as serotonin 5-HT1A and 5-HT2A/C receptors. An anti-parkinson agent.

The Uses of S-(-)-LISURIDE

A dopamine and serotonin receptor partial agonist with high affinity for the dopamine D2, D3 and D4 receptors, as well as serotonin 5-HT1A and 5-HT2A/C receptors. An anti-parkinson agent (1,2).

Background

An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).

Indications

For the management of Parkinson's Disease

Definition

ChEBI: Lisuride is a monocarboxylic acid amide. It has a role as an antiparkinson drug, a serotonergic agonist, a dopamine agonist and an antidyskinesia agent. It derives from a hydride of an ergoline.

Pharmacokinetics

There is evidence that lisuride lowers prolactin levels and, in low doses, prevents migraine attacks.

Metabolism

Not Available

Properties of S-(-)-LISURIDE

Melting point: 186°
Boiling point: 603.4±55.0 °C(Predicted)
alpha  D20 +313° (c = 0.60 in pyridine)
Density  1.23±0.1 g/cm3(Predicted)
pka 13.06±0.20(Predicted)
CAS DataBase Reference 18016-80-3

Safety information for S-(-)-LISURIDE

Computed Descriptors for S-(-)-LISURIDE

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