Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(S)-(-)-2-Methyl-1-butanol

(S)-(-)-2-Methyl-1-butanol

Synonym(s):(S)-(−)-2-Methyl-1-butanol;Active amyl alcohol

  • CAS NO.:1565-80-6
  • Empirical Formula: C5H12O
  • Molecular Weight: 88.15
  • MDL number: MFCD00064299
  • EINECS: 216-366-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-11-28 16:31:43
(S)-(-)-2-Methyl-1-butanol Structural

What is (S)-(-)-2-Methyl-1-butanol?

Chemical properties

clear colourless liquid

The Uses of (S)-(-)-2-Methyl-1-butanol

(S)-(-)-2-Methylbutanol can be used as a reactant to prepare:

  • Methylbutyl-2-(3-thienyl)acetate (MBTA) by esterification reaction with 3-thiophene acetic acid in the presence of an acid catalyst.
  • (2S)-2-Methyl-1-butanesulfenyl chloride by reacting with thioacetic acid using Mitsunobu reaction conditions.
  • (+)-Violapyrone C and (-)-myxalamide A.

The Uses of (S)-(-)-2-Methyl-1-butanol

(S)-(?)-2-Methylbutanol can be used to prepare:

  • (S)-(?)-2-Methyl-1-butyloxy carbonyl amino hexyl isocyanate (MBI), which is used to synthesize isocyanate copolymers.
  • Chiral alkoxynaphathoic acid derivatives having liquid crystalline properties.
  • 3,4-Bis[(S)-2-methylbutoxy]thiophene, a key intermediate for the synthesis of polythiophenes.

Definition

ChEBI: The (S)-enantiomer of 2-methylbutan-1-ol.

General Description

rest mainly 3-methyl-1-butanol

Purification Methods

Reflux the butanol with CaO, distil, reflux with magnesium and again fractionally distil it. A small sample of highly purified material is obtained by fractional crystallisation after conversion into a suitable ester such as the trinitrophthalate or the 3-nitrophthalate. The latter is converted to the cinchonine salt in acetone and recrystallised from CHCl3 by adding pentane. The salt is saponified, extracted with ether, and fractionally distilled. [Terry et al. J Chem Eng Data 5 403 1960, Beilstein 1 IV 1666.]

Properties of (S)-(-)-2-Methyl-1-butanol

Melting point: -70 °C
Boiling point: 136-138 °C(lit.)
alpha  -5.8 º (neat 23 ºC)
Density  0.811 g/mL at 25 °C(lit.)
vapor density  3 (vs air)
vapor pressure  1 mm Hg ( 13.6 °C)
refractive index  n20/D 1.409(lit.)
Flash point: 120 °F
storage temp.  2-8°C
solubility  soluble in Chloroform, Ethanol
pka 15.24±0.10(Predicted)
form  clear liquid
color  Colorless to Almost colorless
Odor ethereal fresh
optical activity [α]23/D 5.8°, neat
Water Solubility  36 g/L (30 ºC)
Merck  14,6030
BRN  1718809
Dielectric constant 15.8(20℃)
CAS DataBase Reference 1565-80-6(CAS DataBase Reference)
NIST Chemistry Reference 1-Butanol, 2-methyl-, (S)-(1565-80-6)
EPA Substance Registry System 1-Butanol, 2-methyl-, (2S)- (1565-80-6)

Safety information for (S)-(-)-2-Methyl-1-butanol

Signal word Warning
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H226:Flammable liquids
H332:Acute toxicity,inhalation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

Computed Descriptors for (S)-(-)-2-Methyl-1-butanol

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.