2,5-Dimethylpyridine

Synonym(s):2,5-Dimethylpyridine

CAS NO.：589-93-5
Empirical Formula: C7H9N
Molecular Weight: 107.15
MDL number: MFCD00006343
EINECS: 209-666-9
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 2,5-Dimethylpyridine?

The Uses of 2,5-Dimethylpyridine

2,5-Lutidine was used to displace CO from the haem iron.

Synthesis Reference(s)

Tetrahedron Letters, 17, p. 383, 1976 DOI: 10.1016/S0040-4039(00)93738-9

General Description

The FT-IR and FT-Raman spectra of 2,5-lutidine was studied.

Purification Methods

Steam distil the lutidine from a solution containing 1-2 equivalents of 20% H2SO4 until about 10% of the base has been carried over with the non-basic impurities, then the acidic solution is made alkaline, and the base is separated, dried with NaOH and fractionally distilled twice. Dry the distillate with Na and fractionally distil it through a Todd column (p 11) packed with glass helices. The hydrochloride has m 219o(dec), and the picrate has m 170.5o (from EtOH or H2O). [Beilstein 20 H 244, 20 II 160, 20 III/IV 2774, 20/6 V 27.]

Properties of 2,5-Dimethylpyridine

Melting point:	−15 °C(lit.)
Boiling point:	157 °C(lit.)
Density	0.926 g/mL at 25 °C(lit.)
vapor pressure	2.4 mm Hg ( 20 °C)
refractive index	n20/D 1.499(lit.)
Flash point:	118 °F
form	clear liquid
pka	6.4(at 25℃)
color	Colorless to Light orange to Yellow
Water Solubility	77g/L(23 ºC)
Sensitive	Hygroscopic
CAS DataBase Reference	589-93-5(CAS DataBase Reference)
NIST Chemistry Reference	Pyridine, 2,5-dimethyl-(589-93-5)
EPA Substance Registry System	2,5-Dimethylpyridine (589-93-5)

Safety information for 2,5-Dimethylpyridine

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.