(S)-1,4-Benzodioxane-2-carboxylic acid

Synonym(s):(S)-2,3-Dihydro-1,4-benzodioxin-2-carboxylic acid

CAS NO.：70918-54-6
Empirical Formula: C9H8O4
Molecular Weight: 180.16
MDL number: MFCD00239408
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-30 16:20:48

(S)-1,4-Benzodioxane-2-carboxylic acid Structural

What is (S)-1,4-Benzodioxane-2-carboxylic acid?

Chemical properties

White crystalline powder

The Uses of (S)-1,4-Benzodioxane-2-carboxylic acid

(S)-2,3-Dihydrobenzo[1,4]dioxine-2-carboxylic Acid is an intermediate used to prepare 2-[4-(1,4-Benzodioxan-2-ylcarbonyl)piperazin-1-yl] derivatives as α1-adrenoceptor antagonists and antihypertensive agents. It is also used to synthesize G protein-coupled receptor antagonists.

Properties of (S)-1,4-Benzodioxane-2-carboxylic acid

Melting point:	96-99 °C
Boiling point:	347.2±41.0 °C(Predicted)
alpha	-83 º (c=1.5% in chloroform)
Density	1.379±0.06 g/cm3(Predicted)
storage temp.	2-8°C
pka	2.69±0.20(Predicted)
optical activity	[α]20/D 83±2°, c = 1.5% in chloroform
BRN	5742836

Safety information for (S)-1,4-Benzodioxane-2-carboxylic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.