RUFLOXACIN
- CAS NO.:101363-10-4
- Empirical Formula: C17H18FN3O3S
- Molecular Weight: 363.41
- MDL number: MFCD00865073
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:30
What is RUFLOXACIN?
Definition
ChEBI: Rufloxacin is a member of quinolines, a quinolone antibiotic and a fluoroquinolone antibiotic.
Pharmaceutical Applications
A tricyclic fluoroquinolone formulated as the hydrochloride salt. It is inactive against Gram-positive cocci with MICs >2 mg/L. It displays weak activity in vitro against Enterobacteriaceae with the MIC for most species >1 mg/L. Activity against Ps. aeruginosa is poor (MIC 16–32 mg/L). After loading doses of 400 and 600 mg followed with 9 days of either 200 or 300 mg, mean peak plasma levels were around 4.5–7 mg/L, respectively. The mean apparent elimination halflife was 44 h. Approximately 50% is eliminated in the urine.
It has been used in urinary tract infection and chronic prostatitis, but clinical experience is limited.
Properties of RUFLOXACIN
Boiling point: | 574.6±50.0 °C(Predicted) |
Density | 1.54 |
storage temp. | 2-8°C |
pka | 5.21±0.20(Predicted) |
CAS DataBase Reference | 101363-10-4 |
Safety information for RUFLOXACIN
Computed Descriptors for RUFLOXACIN
New Products
Tubulysin E Tubulysin C Tubulysin A Potassium HMDS (1.0 M in THF) 4-CYANO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE 4-(Benzyloxy)-3-bromophenylacetic Acid 2H-Pyran, 4-ethynyltetrahydro- Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 3-Aminocyclobutanone hydrochloride (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Imeglimin Hydrochloride IH Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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