(R)-(+)-BETA-CITRONELLOL

Synonym(s):(+)-β-Citronellol;(R)-3,7-Dimethyl-6-octen-1-ol

CAS NO.：1117-61-9
Empirical Formula: C10H20O
Molecular Weight: 156.27
MDL number: MFCD00063215
EINECS: 214-250-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-09 19:38:33

What is (R)-(+)-BETA-CITRONELLOL?

Description

(+)-β-Citronellol is a monoterpene that has been found in Cannabis. It inhibits degranulation of cultured mast cells by 21.3% when used at a concentration of 0.5 mM. Unlike (R)-citronellal, it does not reduce the perceived bitterness of caffeine when used at a concentration of 5.9 nM. Formulations containing (+)-β-citronellol have been used as fragrance ingredients in various cosmetics, toiletries, and cleaning products.

The Uses of (R)-(+)-BETA-CITRONELLOL

(R)-(+)-β-Citronellol can undergo:

Oxidation to form (R)-(+)-citronellal, an antifungal agent and (R)-(+)-citronellic acid.
Intermolecular olefin aziridination with 2,2,2-trichloroethoxysulfonamide to form citronellol aziridine for ring-opening reactions.
Series of reactions to form α2δ-ligands for treating generalized anxiety disorder and insomnia.

Definition

ChEBI: A citronellol that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7 (the 3R-enantiomer).

Properties of (R)-(+)-BETA-CITRONELLOL

Melting point:	-4.05°C (estimate)
Boiling point:	112-113 °C12 mm Hg(lit.)
Density	0.857 g/mL at 25 °C(lit.)
vapor pressure	~0.02 mm Hg ( 25 °C)
refractive index	n20/D 1.456(lit.)
Flash point:	213 °F
storage temp.	2-8°C
solubility	Chloroform (Sparingly, Sonicated), Ethyl Acetate, Methanol (Slightly)
form	Oil
pka	15.13±0.10(Predicted)
color	Colourless
Odor	at 100.00 %. citronella oil rose leaf oily petal
optical activity	[α]19/D +5.3°, neat
BRN	1721506
CAS DataBase Reference	1117-61-9(CAS DataBase Reference)
EPA Substance Registry System	6-Octen-1-ol, 3,7-dimethyl-, (3R)- (1117-61-9)

Safety information for (R)-(+)-BETA-CITRONELLOL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.