Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(R)-(-)-2-Aminobutane

(R)-(-)-2-Aminobutane

Synonym(s):(R)-(−)-2-Aminobutane

  • CAS NO.:13250-12-9
  • Empirical Formula: C4H11N
  • Molecular Weight: 73.14
  • MDL number: MFCD00064416
  • EINECS: 236-232-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
(R)-(-)-2-Aminobutane Structural

What is (R)-(-)-2-Aminobutane?

Chemical properties

Colorless to light yellow liqui

The Uses of (R)-(-)-2-Aminobutane

(R)-(-)-2-Aminobutane is a chiral amine plays an important role in pharmaceutical chemistry and in organic synthesis as chiral auxiliary, which is used to determine the enantiomeric excess (ee).

The Uses of (R)-(-)-2-Aminobutane

(R)-(?)-sec-Butylamine can be used:

  • To prepare (R)-(?)-sec-butylbis(2-hydroxyethyl)amine, an intermediate for the synthesis of aminodiphosphine ligands.
  • As a substrate to demonstrate the stereochemistry of Mitsunobu reaction in the synthesis of secondary amines.
  • As a model compound in the study of singlet-triplet transitions in circular dichroism.

Purification Methods

Dry it over solid NaOH overnight and fractionate it through a short helices packed column. The L-hydrogen tartrate salt has m 139-140o (from H2O), the 1H2O has m 96o []D +18.1o (c 11, H2O), the hydrochloride has m 152o [ ] 21 -1.1o (c 13, H2O) and the benzoyl derivative crystallises from EtOH as needles with m 97o, [] 21 -34.9o (c 11, H2O). [Bruck et al. J Chem Soc 921 1956,Kjaer & Hansen Acta Chem Scand 11 898 1957.] [Beilstein 4 H 161, 4 I 372, 4 III 308, 4 IV 617.] The S -(+)-enantiomer has has same properties except for the optical rotation which has the opposite sign.

Properties of (R)-(-)-2-Aminobutane

Melting point: -105°C
Boiling point: 63 °C(lit.)
alpha  -7.5 º (c=neat 19 ºC)
Density  0.72 g/mL at 25 °C(lit.)
refractive index  n20/D 1.393(lit.)
Flash point: -19°C
storage temp.  Flammables area
form  clear liquid
pka 10.74±0.10(Predicted)
color  Colorless to Almost colorless
optical activity [α]19/D 7.5°, neat
Water Solubility  > 10 mg/L
Sensitive  Air Sensitive
Merck  14,1544
BRN  1718760
CAS DataBase Reference 13250-12-9(CAS DataBase Reference)

Safety information for (R)-(-)-2-Aminobutane

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H225:Flammable liquids
H314:Skin corrosion/irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (R)-(-)-2-Aminobutane

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.