QX-314
Synonym(s):N-(2,6-Dimethylphenylcarbamoylmethyl)triethylammonium bromide;QX-314;QX-314 - CAS 21306-56-9 - Calbiochem
- CAS NO.：21306-56-9
- Empirical Formula: C16H27N2O+
- Molecular Weight: 263.4
- MDL number: MFCD00083182
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-04 20:04:50
What is QX-314?
The Uses of QX-314
QX-314 bromide is a derivative of Lidocaine. It is a local anesthetic.
The Uses of QX-314
Blocker of voltage-activated sodium channels
What are the applications of Application
QX-314 is a sodium channel protein inhibitor
Biological Activity
Membrane impermeable quaternary derivative of lidocaine, a blocker of voltage-activated Na + channels. Intracellular QX 314 bromide also inhibits calcium currents in hippocampal CA1 pyramidal neurons.
Properties of QX-314
| Melting point: | 220 - 222°C |
| storage temp. | Desiccate at RT |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| color | White to Off-White |
| Specific Activity | 40-60 Ci/mmol |
| Solvent | Ethanol:water (1:1) |
| Concentration | 1 mCi/ml |
Safety information for QX-314
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for QX-314
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