Pyrimidinetetramine sulfate
- CAS NO.：5392-28-9
- Empirical Formula: C4H10N6O4S
- Molecular Weight: 238.22
- MDL number: MFCD00012786
- EINECS: 226-393-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is Pyrimidinetetramine sulfate?
Chemical properties
Light yellow crystal powder
The Uses of Pyrimidinetetramine sulfate
Intermediate in the production of Methotrexate
The Uses of Pyrimidinetetramine sulfate
2,4,5,6-Tetraaminopyrimidine Sulfate is an intermediate for the synthesis of the antitumor drugs methotrexate and fludarabine.
Purification Methods
Purify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.]
References
[1] SAUMYA SHUKLA. Toxic potential assessment of hair dye developer 2,4,5,6-tetraaminopyrimidine sulfate exposed under ambient UVB radiation.[J]. Toxicology and Industrial Health, 2024: 1-8. DOI:10.1177/07482337231209352.
[2] https://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_o_152.pdf
Properties of Pyrimidinetetramine sulfate
| Melting point: | >300 °C(lit.) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Water (Very Slightly, Heated) |
| form | Crystalline Powder |
| color | Ochre to brown |
| Water Solubility | slightly soluble |
| BRN | 3785189 |
| CAS DataBase Reference | 5392-28-9(CAS DataBase Reference) |
| EPA Substance Registry System | Pyrimidinetetramine, sulfate (1:1) (5392-28-9) |
Safety information for Pyrimidinetetramine sulfate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for Pyrimidinetetramine sulfate
| InChIKey | MQEFDQWUCTUJCP-UHFFFAOYSA-N |
Abamectin manufacturer
Medilux Laboratories Pvt Ltd
1Y
Phone:+919819666688
Whatsapp: +91- 9819666688
product: 2,4,5,6-Tetraamino pyrimidine sulfate 5392-28-9 98%
Anand Agencies
Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: 2,4,5,6-Tetraamino pyrimidine sulfate
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 2,4,5,6-Tetraamino pyrimidine sulfate
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
You may like
-
5392-28-9 2,4,5,6-Tetramino Pyridine Sulfate 98%View Details
5392-28-9 -
5392-28-9 99%View Details
5392-28-9 -
2,4,5,6-Tetraamino pyrimidine sulfate 98%View Details
5392-28-9 -
2,4,5,6-Tetraamino pyrimidine sulfate 5392-28-9 98%View Details
5392-28-9 -
2,4,5,6-Tetraaminopyrimidine Sulfate CAS 5392-28-9View Details
5392-28-9 -
Pyrimidine-2,4,5,6-tetraamine sulfate 90% CAS 5392-28-9View Details
5392-28-9 -
2,4,5,6-Tetraaminopyrimidine sulfate salt CAS 5392-28-9View Details
5392-28-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.