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HomeProduct name listPYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

Synonym(s):(D-Ala-6) Luteinizing Hormone Releasing Hormone

PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2 Structural

What is PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2?

The Uses of PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

[D-Ala6]-LH-RH acetate salt hydrate has been used to induce ovulation and to synchronize the reproductive cycle in Sprague-Dawley female rats.

Biochem/physiol Actions

(D-Ala6)-LH-RH is a GnRH (gonadotropin-releasing hormone) agonist. GnRH, which is also referred to as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism.

Properties of PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

Density  1.52±0.1 g/cm3(Predicted)
storage temp.  −20°C
pka 9.82±0.15(Predicted)

Safety information for PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

Signal word Danger
Pictogram(s)
ghs
Health Hazard
GHS08
GHS Hazard Statements H360:Reproductive toxicity
Precautionary Statement Codes P201:Obtain special instructions before use.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for PYR-HIS-TRP-SER-TYR-D-ALA-LEU-ARG-PRO-GLY-NH2

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