PTZ-343

CAS NO.：101199-38-6
Empirical Formula: C15H16NNaO3S2
Molecular Weight: 345.41
MDL number: MFCD08275674
EINECS: 1592732-453-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-09 19:38:33

What is PTZ-343?

Description

PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.

The Uses of PTZ-343

Sodium 3-?(10H-?Phenothiazin-?10-?yl)?propane-?1-?sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum.

in vitro

PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission.

Properties of PTZ-343

Melting point:	>232°C (dec.)
storage temp.	Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility	DMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated)
form	Solid
color	Off-White to Pale Yellow
Stability:	Hygroscopic
InChI	InChI=1S/C15H15NO3S2.Na.H/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;;/h1-4,6-9H,5,10-11H2,(H,17,18,19);;

Safety information for PTZ-343

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.