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HomeProduct name listPTZ-343

PTZ-343

  • CAS NO.:101199-38-6
  • Empirical Formula: C15H16NNaO3S2
  • Molecular Weight: 345.41
  • MDL number: MFCD08275674
  • EINECS: 1592732-453-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
PTZ-343 Structural

What is PTZ-343?

Description

PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.

The Uses of PTZ-343

Sodium 3-?(10H-?Phenothiazin-?10-?yl)?propane-?1-?sulfonate can be used in biological and analytical studies of a portable chemiluminescence imaging immunoassay for simultaneous detection of different isoforms of prostate specific antigen in serum.

in vitro

PTZ-343 behaves as electron transfer mediator, it reacts with HRP-II to release HRP and a enhance (PTZ-343) radical. The enhancer (PTZ-343) radical quickly oxidizes luminol anions to induce light emission.

Properties of PTZ-343

Melting point: >232°C (dec.)
storage temp.  Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility  DMSO (Slightly), Methanol (Slightly), Water (Slightly, Heated)
form  Solid
color  Off-White to Pale Yellow
Stability: Hygroscopic
InChI InChI=1S/C15H15NO3S2.Na.H/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;;/h1-4,6-9H,5,10-11H2,(H,17,18,19);;

Safety information for PTZ-343

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for PTZ-343

InChIKey LAXVHQHEZUKIAE-UHFFFAOYSA-N
SMILES C(N1C2=CC=CC=C2SC2C=CC=CC1=2)CCS(O)(=O)=O.[NaH]

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