psoralidin
Synonym(s):3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one;3,9-Dihydroxy-2-prenylcoumestan
- CAS NO.:18642-23-4
- Empirical Formula: C20H16O5
- Molecular Weight: 336.34
- MDL number: MFCD10566617
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 19:05:58
What is psoralidin?
Description
Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-
The Uses of psoralidin
Psoralidin is an antibacterial and antioxidant reagent.
What are the applications of Application
Psoralidin is an antibacterial and antioxidant reagent
Definition
ChEBI: A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.
References
[1] yang h j, youn h s, seong k m, et al. psoralidin, a dual inhibitor of cox-2 and 5-lox, regulates ionizing radiation (ir)-induced pulmonary inflammation[j]. biochemical pharmacology, 2011, 82(5): 524-534.
[2] chiou w f, don m j, liao j f, et al. psoralidin inhibits lps-induced inos expression via repressing syk-mediated activation of pi3k-ikk-iκb signaling pathways[j]. european journal of pharmacology, 2011, 650(1): 102-109.
[3] bronikowska j, szliszka e, jaworska d, et al. the coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (trail)[j]. molecules, 2012, 17(6): 6449-6464.
Properties of psoralidin
Melting point: | 290-292° |
Boiling point: | 458.8±34.0 °C(Predicted) |
Density | 1.383±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | DMSO: soluble5mg/mL, clear (warmed) |
form | powder |
pka | 8.70±0.20(Predicted) |
color | white to beige |
Safety information for psoralidin
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for psoralidin
InChIKey | YABIJLLNNFURIJ-UHFFFAOYSA-N |
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