TYROSINASE
Synonym(s):Catechol Oxidase;Monophenol Monooxygenase;Monophenol, dihydroxyphenylalanine:oxygen oxidoreductase;Polyphenol Oxidase
- CAS NO.：9002-10-2
- Empirical Formula: NULL
- Molecular Weight: 0
- MDL number: MFCD00082118
- EINECS: 232-653-4
- Update Date: 2024-07-02 08:55:01
What is TYROSINASE?
The Uses of TYROSINASE
Tyrosinase activity has been assessed in a study that developed an alternative therapeutic agent for treating hyperpigmentation. Tyrosinase has also been used in a study to investigate the oculocutaneous albinism phenotype in the Pakistani population.
General Description
Isoelectric point (pI): 4.7-5
pH optimum is 6-7
Molecular weight: 128 kDa by sedimentation velocity diffusion; 133?kDa by light-scattering measurements, and 119.5 kDa by electrophoresis.
Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. The enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. The copper is probably Cu(I), with inactivation involving oxidation to Cu(II) ion.
Biochem/physiol Actions
Converts tyrosine to L-DOPA or tyramine to dopamine
Properties of TYROSINASE
| Melting point: | 89-94 °C |
| storage temp. | -20°C |
| form | lyophilized powder |
| color | Light brown to brown |
| CAS DataBase Reference | 9002-10-2 |
| EPA Substance Registry System | Oxygenase, monophenol mono- (9002-10-2) |
Safety information for TYROSINASE
| Signal word | Danger |
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P284:Wear respiratory protection. P501:Dispose of contents/container to..… |
Computed Descriptors for TYROSINASE
New Products
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