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HomeProduct name listPseudohypericin

Pseudohypericin

Pseudohypericin Structural

What is Pseudohypericin?

The Uses of Pseudohypericin

Pseudohypericin is a specific inhibitor of protein kinase C and D-β-Hydroxylase. Also, it is used in determination of potential drug candidate molecules of Hypericum perforatum for COVID-19 treatment.

What are the applications of Application

Pseudohypericin is a specific inhibitor of PKC (protein kinase C) and DBH (D-β-Hydroxylase)

Definition

ChEBI: Pseudohypericin is an ortho- and peri-fused polycyclic arene.

Enzyme inhibitor

This anti-retroviral agent (FW = 520.45 g/mol) inhibits protein kinase C with an IC50 value of 28.7 μM and dopamine b-hydroxylase with IC50 = 3 μM. Pseudohypericin is a component of St. John’s Wort (Hypericum perforatum). Target(s): dopamine b-hydroxylase; inositoltrisphosphate 3-kinase; and protein kinase C.

Properties of Pseudohypericin

Boiling point: 1089.1±65.0 °C(Predicted)
Density  1.994±0.06 g/cm3(Predicted)
storage temp.  2-8°C
form  powder
pka 7.16±0.20(Predicted)
color  brown
CAS DataBase Reference 55954-61-5(CAS DataBase Reference)

Safety information for Pseudohypericin

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for Pseudohypericin

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