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HomeProduct name listPROTRIPTYLINE HYDROCHLORIDE

PROTRIPTYLINE HYDROCHLORIDE

Synonym(s):N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine hydrochloride

  • CAS NO.:1225-55-4
  • Empirical Formula: C19H22ClN
  • Molecular Weight: 299.84
  • MDL number: MFCD00072057
  • EINECS: 214-956-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-11 20:33:26
PROTRIPTYLINE HYDROCHLORIDE Structural

What is PROTRIPTYLINE HYDROCHLORIDE?

The Uses of PROTRIPTYLINE HYDROCHLORIDE

Monoamine reuptake inhibitor; tricyclic antidepressant.

What are the applications of Application

Protriptyline hydrochloride is A norepinephrine uptake blocker

brand name

Vivactil (Odyssey).

General Description

Protriptyline hydrochloride, N-methyl-5H-dibenzo[a,d]-cycloheptene-5-propylamine hydrochloride, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene hydrochloride(Vivactil), like the other compounds under consideration, isan effective antidepressant. The basis for its chemical namingcan be seen by consulting the naming and the structureof imipramine. Protriptyline is a structural isomer of nortriptyline.Inactivation can be expected to involve the relativelylocalized double bond. Because it is a monomethylcompound, its sedative potential is low.

Biochem/physiol Actions

Norepinephrine uptake blocker.

Properties of PROTRIPTYLINE HYDROCHLORIDE

Melting point: 169-171°
Flash point: 9℃
storage temp.  2-8°C
solubility  H2O: soluble50mg/mL
form  powder
pka 8.2(at 25℃)
color  white to off-white
Stability: Hygroscopic

Safety information for PROTRIPTYLINE HYDROCHLORIDE

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for PROTRIPTYLINE HYDROCHLORIDE

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