PROCYANIDIN B2
Synonym(s):(−)-Epicatechin (4β-8)-(−)-epicatechin;cis,cis″-4,8″-Bi(3,3′,4′,5,7-pentahydroxyflavane);4,8″-Bi-[(+)-epicatechin];Proanthocyanidin B2
- CAS NO.:29106-49-8
- Empirical Formula: C30H26O12
- Molecular Weight: 578.52
- MDL number: MFCD01861513
- EINECS: 000-000-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is PROCYANIDIN B2?
The Uses of PROCYANIDIN B2
Procyanidin B2 is a selective protein kinase C inhibitor and was also found to promote hair epithelial cell growth and stimulate anagen induction. Procyanidin B2 extracted from apples have also shown anti-inflammatory activities.
The Uses of PROCYANIDIN B2
Procyanidin B2 is a selective protein kinase C inhibitor and was also found to promote hair epithelial cell growth and stimulate anagen induction. Procyanidin B2 extracted from apples have also shown anti-inflammatory activities.
Definition
ChEBI: Procyanidin B2 is a proanthocyanidin consisting of two molecules of (-)-epicatechin joined by a bond between positions 4 and 8' in a beta-configuration. Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chinensis (litchi, in the pericarp), in the apple, in Ecdysanthera utilis and in red wine. It has a role as a metabolite and an antioxidant. It is a hydroxyflavan, a proanthocyanidin, a biflavonoid and a polyphenol. It is functionally related to a (-)-epicatechin.
Properties of PROCYANIDIN B2
Melting point: | 197-198℃ |
Boiling point: | 955.3±65.0 °C(Predicted) |
Density | 1.705 |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
pka | 9.29±0.60(Predicted) |
form | neat |
form | Solid |
color | Light Red to Brown |
Stability: | Hygroscopic |
Safety information for PROCYANIDIN B2
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for PROCYANIDIN B2
InChIKey | XFZJEEAOWLFHDH-NFJBMHMQSA-N |
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