Prasugrel Hydrochloride
- CAS NO.:389574-19-0
- Empirical Formula: C20H20FNO3S.ClH
- Molecular Weight: 409.907
- MDL number: MFCD11867705
- EINECS: 627-126-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 15:41:55
What is Prasugrel Hydrochloride?
Description
Prasugrel hydrochloride (PCR 4099 hydrochloride), a thienopyridine and proagent, inhibits platelet function. Prasugrel hydrochloride is an orally active and potent P2Y12 receptor antagonist and inhibits ADP-induced platelet aggregation.
Chemical properties
White to Off-White Solid
The Uses of Prasugrel Hydrochloride
A novel antiplatelet agent; it is a third-generation thienopyridine. y induce increased incidence of bleeding in patient with acute coronary syndrome
The Uses of Prasugrel Hydrochloride
A novel antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome
What are the applications of Application
Prasugrel Hydrochloride is an antiplatelet agent that binds to P2Y receptors
in vivo
In rat platelets, Prasugrel hydrochloride active metabolite inhibits in vitro platelet aggregation induced by adenosine ADP (10μM) with an IC50 value of 1.8 μM. Prasugrel hydrochloride acts faster and is significantly more potent than Clopidogrel in vivo. Prasugrel hydrochloride is an inactive prodrug that requires metabolic processing in vivo to generate the active antiplatelet metabolite. Prasugrel hydrochloride is rapidly absorbed from the gut. After oral administration of standard-loading doses of 60 mg, maximum plasma levels of the active metabolite are achieved within 1 h, effective, maximum inhibition of platelet aggregation at 1-2 h.
Properties of Prasugrel Hydrochloride
Melting point: | >173?C (dec.) |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly) |
form | Solid |
color | White to Pale Brown |
InChI | InChI=1S/C20H20FNO3S.ClH/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21;/h2-5,10,13,19H,6-9,11H2,1H3;1H |
Safety information for Prasugrel Hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Prasugrel Hydrochloride
InChIKey | JALHGCPDPSNJNY-UHFFFAOYSA-N |
SMILES | N1(CCC2SC(OC(C)=O)=CC=2C1)C(C1C=CC=CC=1F)C(=O)C1CC1.Cl |
Abamectin manufacturer
KARPSCHEM LABORATORIES PVT. LTD.
Lupin Ltd
Macleods Pharmaceuticals Limited
Lee Pharma Ltd
Megafine Pharma
New Products
Bromine 99.5% AR (4 x 500ml) Fehling's Solution No. B Amino Acid Kit of 23 items set Ammonium Molybdate Reagent Solution Beam's Reagent Solution Ehrlich's Reagent For detection of urobillinogen 4-Hydroxy Carbazole 4-((2-isopropoxyethoxy)methyl)phenol 2 – Methoxy – 5- Sulfamoyl Benzoic acid Amino Salicylic Acid. U.S.P. 1,2,3,4-Tetrahydrocarbazol-4-one Acetone Isobutryl oxime ester Curcuma aromatica Oil Curry leaf Extract Terminalia bellirica Extract Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract (S)-4-(4-(5-(Aminomethyl)-2-Oxooxazolidin-3-Yl)Phenyl)Mo Ethyl N-[[2-[[[4-(Aminoiminomethyl)Phenyl]Amino]Methyl] 5-Nitrosalicylaldehyde 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole- IP/BP/ Cypermethric Acid Chloride Methyl Di Chloride (Mdc)Related products of tetrahydrofuran
You may like
-
389574-19-0 98%View Details
389574-19-0 -
Prasugrel Hydrochloride 99%View Details
-
Prasugrel hydrochloride 95% CAS 389574-19-0View Details
389574-19-0 -
389574-19-0 Prasugrel Hydrochloride 98%View Details
389574-19-0 -
Prasugrel Hydrochloride 389574-19-0 98%View Details
389574-19-0 -
Prasugrel Hydrochloride 389574-19-0 98%View Details
389574-19-0 -
Prasugrel Hydrochloride CAS 389574-19-0View Details
389574-19-0 -
Prasugrel Hydrochloride CAS 389574-19-0View Details
389574-19-0