Potassium sodium tartrate tetrahydrate

Synonym(s):L(+)-Tartaric acid potassium Sodium salt;Potassium sodium tartrate tetrahydrate;Rochelle salt;Seignette salt;Sodium potassium tartrate, Tartaric acid potassium sodium salt

CAS NO.：6381-59-5
Empirical Formula: C4H12KNaO10
Molecular Weight: 282.22
MDL number: MFCD00150989
EINECS: 613-385-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-21 17:11:28

Potassium sodium tartrate tetrahydrate Structural

What is Potassium sodium tartrate tetrahydrate?

Chemical properties

white semi-transparent crystals

The Uses of Potassium sodium tartrate tetrahydrate

Potassium sodium tartrate tetrahydrate has been used in the preparation of Lowry reagent for the determination of microsomal protein concentration in rat hepatic microsomes by Lowry method. It may be used as a constituent to prepare DNS (3,5- dinitrosalicylic acid) reagent and Fehling′s solution B, which are used in the determination of reducing sugar.

The Uses of Potassium sodium tartrate tetrahydrate

Constituent of Fehling's solution

The Uses of Potassium sodium tartrate tetrahydrate

Potassium sodium tartrate tetrahydrate has been used in the preparation of 3,5-dinitrosalicylic acid solution used in the determination of the reducing sugar.

What are the applications of Application

Potassium sodium tartrate tetrahydrate is used in protein crystallization, organic synthesis, making μm aerosol particles.

Preparation

Potassium sodium tartrate tetrahydrate is obtained by the follow steps:The starting material is tartar with a minimum tartaric acid content 68 %. This is first dissolved in water or in the mother liquor of a previous batch. It is then basified with hot saturated sodium hydroxide solution to pH 8, decolorized with activated charcoal, and chemically purified before being filtered. The filtrate is evaporated to 42 °Bé at 100 °C, and passed to granulators in which Seignette's salt crystallizes on slow cooling. The salt is separated from the mother liquor by centrifugation, accompanied by washing of the granules.

General Description

Potassium sodium tartrate tetrahydrate is a ferroelectric crystal with a high piezoelectric effect and electromechanical coupling coefficient.

Biochem/physiol Actions

Potassium sodium tartrate tetrahydrate might be used as a buffering agent in cosmetic products. It is also used as a food additive. Certain studies show that it produces acute renal toxicity in rabbits and dogs.

Purification Methods

Recrystallise it from distilled water (solubility: 0.4mL/g at 100o, 0.7mL/g at 14o). [Beilstein 3 IV 1223.]

Properties of Potassium sodium tartrate tetrahydrate

Melting point:	70-80 °C
Boiling point:	220°C
alpha	22.1 º (c=10, water)
Density	1.05 g/mL at 20 °C
refractive index	22 ° (C=10, H2O)
storage temp.	Store at +5°C to +30°C.
solubility	H₂O: 1 M at 20 °C, clear, colorless
form	Solid
appearance	Colorless solid
color	White semi-transparent
Odor	Odorless
PH	7.0-8.5 (25℃, 50mg/mL in H2O)
PH Range	6.0 - 8.5
optical activity	[α]20/D +28.0 to +30.0°
Water Solubility	630 g/L (20 ºC)
λmax	λ: 260 nm Amax: 0.026 λ: 280 nm Amax: 0.022
Merck	14,7670
BRN	6113568
CAS DataBase Reference	6381-59-5(CAS DataBase Reference)
NIST Chemistry Reference	Sodium potassium tartrate tetrahydrate(6381-59-5)

Safety information for Potassium sodium tartrate tetrahydrate

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.