Poly(sodium 4-styrenesulfonate)

Chemical properties

white to tan powder

The Uses of Poly(sodium 4-styrenesulfonate)

Scale inhibitor and dispersant for metal salts and oxides.Anionic polyelectrolyte.

The Uses of Poly(sodium 4-styrenesulfonate)

Poly(sodium 4-styrenesulfonate) is a film former. It holds the actives on site and gives the feeling of skin tightening. It is synthetically manufactured.

Definition

ChEBI: A polymer composed of repeating sodium 4-ethylbenzenesulfonate units.

General Description

Poly (sodium 4-styrenesulfonate) (PSS) a cation exchange polyelectrolyte. PSS may be used to produce mechanically stable and very reproducible coatings.

Clinical Use

Poly(sodium 4-styrenesulfonate), also named as polystyrene sulfonate, is a water-soluble polymer. It has sulfonate groups and mostly used as ion-exchange resins to remove ions such as potassium, calcium, sodium from solutions in biomedical applications. PSS is commonly used as potassium ions binder to cure chronic and acute kidney disease in people suffering hyperkalemia.30 PSS may have side effects when it is blended with sorbitol, causing intestinal necrosis[1].

Safety Profile

Mildly toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and Na2O. See also SULFONATES.

Purification Methods

Purify the polymer by repeated precipitation of the sodium salt from an aqueous solution by MeOH, with subsequent conversion to the free acid by passage through an Amberlite IR-120 ion-exchange resin. [Kotin & Nagasawa J Am Chem Soc 83 1026 1961.] Recrystallise it from EtOH. Alternatively purify it by passage through cation and anion exchange resins in series (Rexyn 101 cation exchange resin and Rexyn 203 anion exchange resin), then titrated it with NaOH to pH 7. The sodium form of polystyrenesulfonic acid is precipitated by addition of 2-propanol. Dry it in a vacuum oven at 80o for 24hours, and finally increasing to 120o before to use. [Kowblansky & Ander J Phys Chem 80 297 1976.]

References

[1] Sarwar M, et al. Development and characterization of sodium alginate/poly(sodium 4-styrenesulfonate) composite films for release behavior of ciprofloxacin hydrogen chloride monohydrate. Polymers and Polymer Composites, 2021.