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HomeProduct name listPirmenol hydrochloride

Pirmenol hydrochloride

Pirmenol hydrochloride Structural

What is Pirmenol hydrochloride?

Description

Pirrnenol hydrochloride is a long-lasting Class la antiarrhythmic agent introduced in Japan in 1994. The spectrum of antiarrhythmic activity of pirmenol includes atrial and ventricular arrhythmias of diverse etiology. In clinical trials, pirmenol was found effective in the short- and mid-term treatment of chronic premature ventricular beats, with or without underlying heart disease. In patients with supraventricular tachycardia, a single oral dose of pirmenol was highly effective in suppressing induction of tachycardia with adequate hemodynamic tolerance. Since pirmenol is highly effective by both intravenous and oral routes, it enables immediate suppression, prevention, or termination of cardiac arrhythmias and facilitates the transition to oral prophylactic therapy.

Originator

Warner-Lamber (U.S.A.)

The Uses of Pirmenol hydrochloride

Cardiac depressant (anti-arrhythmic).

brand name

Pirmavar (Parke-Davis);Plmenol.

Properties of Pirmenol hydrochloride

Melting point: 171-172 °C
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO : ≥ 28 mg/mL (74.68 mM)
form  Solid
color  White to yellow

Safety information for Pirmenol hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Pirmenol hydrochloride

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