Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listPiperonylic acid

Piperonylic acid

Synonym(s):1,3-Benzodioxole-5-carboxylic acid;3,4-(Methylenedioxy)benzoic acid

  • CAS NO.:94-53-1
  • Empirical Formula: C8H6O4
  • Molecular Weight: 166.13
  • MDL number: MFCD00005830
  • EINECS: 202-342-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-06 18:33:45
Piperonylic acid Structural

What is Piperonylic acid?

Chemical properties

white to light yellow crystal powde

The Uses of Piperonylic acid

Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.

Definition

ChEBI: Piperonylic acid is a member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a carboxy group at position 5. It is a natural product isolated from several plant species. It is a selective mechanism-based inactivator of the trans-cinnamate 4-hydroxylase enzyme and exhibits antifungal and skin wound healing properties. It has a role as a plant metabolite, an EC 1.14.14.91 ( trans-cinnamate 4-monooxygenase) inhibitor, a vulnerary and an antifungal agent. It is a member of benzodioxoles, a monocarboxylic acid and an aromatic carboxylic acid. It is a conjugate acid of a piperonylate.

Synthesis Reference(s)

The Journal of Organic Chemistry, 40, p. 3803, 1975 DOI: 10.1021/jo00913a051

Purification Methods

Crystallise the acid from EtOH or water. [Beilstein 19/7 V 300.]

Properties of Piperonylic acid

Melting point: 229-231 °C (lit.)
Boiling point: 254.32°C (rough estimate)
Density  1.3579 (rough estimate)
refractive index  1.5090 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka 4.35±0.20(Predicted)
form  Powder
color  Off-white to beige
Water Solubility  slightly soluble
Merck  14,7477
BRN  150206
CAS DataBase Reference 94-53-1(CAS DataBase Reference)
NIST Chemistry Reference 1,3-Benzodioxole-5-carboxylic acid(94-53-1)
EPA Substance Registry System 1,3-Benzodioxole-5-carboxylic acid (94-53-1)

Safety information for Piperonylic acid

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for Piperonylic acid

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.