Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt

Synonym(s):1,4-Piperazinediethanesulfonic acid dipotassium salt;Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt

CAS NO.：108321-27-3
Empirical Formula: C8H19KN2O6S2
Molecular Weight: 342.47
MDL number: MFCD00069751
SAFETY DATA SHEET (SDS)
Update Date: 2023-08-02 17:51:52

Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt Structural

What is Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt?

Chemical properties

White crystalline powder

The Uses of Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt

PIPES (1,4-Piperazinediethanesulfonic acid) dipotassium salt has been used as buffer for fluorescence polarization microscopy studies of kinesin-microtubule binding. It is suitable for use as a component of PHEM buffer ([K-PIPES], HEPES, EGTA, and MgSO4) used during rinsing and blocking steps in immunofluorescence imaging of HeLa cells. It is also suitable for use as buffer for purification of tubulin.

What are the applications of Application

PIPES dipotassium salt is Piperazine-1,4-bis(2-ethanesulfonic acid) dipotassium salt

General Description

PIPES (1,4-Piperazinediethanesulfonic acid) is a zwitterionic buffer. It is a stable buffer and is used majorly in fixation solutions. PIPES is inert towards enzymatic and non-enzymatic reactions. However, it generates artefacts in transmission electron microscope imaging.

Properties of Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt

storage temp.	Store at RT.
solubility	H₂O: 0.5 g/mL, clear, colorless
pka	6.8(at 25℃)
PH Range	6.1 - 7.5
CAS DataBase Reference	108321-27-3(CAS DataBase Reference)
EPA Substance Registry System	1,4-Piperazinediethanesulfonic acid, dipotassium salt (108321-27-3)

Safety information for Piperazine-N,N'-bis-(2-ethanesulphonic acid) dipotassium salt

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.