Perfluoropropionic acid
Synonym(s):2,2,3,3,3-Pentafluoropropionic acid;Perfluoropropionic acid
- CAS NO.：422-64-0
- Empirical Formula: C3HF5O2
- Molecular Weight: 164.03
- MDL number: MFCD00004170
- EINECS: 207-021-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:42:51
What is Perfluoropropionic acid?
Chemical properties
Perfluoropropionic acid (PFPrA[2]) or pentafluoropropionic acid is the perfluoroalkyl carboxylic acid with the formula CF3CF2CO2H. It is a clear colourless to slightly brown liquid that is strongly acidic and soluble in water and polar organic solvents.
The Uses of Perfluoropropionic acid
Pentafluoropropionic acid (Perfluoropropionic acid) was used in the analysis of gentamicin with Gemini column by liquid chromatographic (LC) methods.
The Uses of Perfluoropropionic acid
Pentafluoropropionic acid is used as an efficient catalyst for the preparation of dibenzo[a, j] xanthenes by condensation reaction of beta-naphthol with aryl aldehydes.
General Description
The kinetics of the reaction of pentafluoropropionic acid with fluorine atoms was studied.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes of Fí.
Properties of Perfluoropropionic acid
| Boiling point: | 96-97 °C (lit.) |
| Density | 1.561 g/mL at 25 °C (lit.) |
| vapor density | ~5.6 (vs air) |
| vapor pressure | ~40 mm Hg ( 20 °C) |
| refractive index | n |
| Flash point: | None |
| storage temp. | Store below +30°C. |
| Water Solubility | Soluble in water |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Liquid |
| pka | 0.38±0.10(Predicted) |
| Specific Gravity | 1.561 |
| color | Clear colorless to slightly brown |
| Sensitive | Hygroscopic |
| BRN | 1773387 |
| Stability: | hygroscopic |
| CAS DataBase Reference | 422-64-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Pentafluoropropionic acid(422-64-0) |
| EPA Substance Registry System | Pentafluoropropionic acid (422-64-0) |
Safety information for Perfluoropropionic acid
| Signal word | Danger |
| Pictogram(s) |
 Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H290:Corrosive to Metals H314:Skin corrosion/irritation H331:Acute toxicity,inhalation |
| Precautionary Statement Codes |
P234:Keep only in original container. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Perfluoropropionic acid
| InChIKey | LRMSQVBRUNSOJL-UHFFFAOYSA-N |
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