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Peimine

Peimine Structural

What is Peimine?

Description

Fritillaria verticillata var. Thunbergii also yields this steroidal alkaloid which was originally given the formulae ClsH3302N or C19H3S02N. The base has [α]10D -10.66° (EtOH), yields a crystalline perchlorate, a platinichloride, and contains three non-phenolic hydroxyl groups. The nitrogen atom is tertiary in character. Chi and his colleagues regard the alkaloid as identical with Peimine (q.v.).

The Uses of Peimine

Peimine is a steroidal alkaloid compound extracted from the Fritillaria species of medicinal plants.

Definition

ChEBI: Verticine is an alkaloid.

References

Fukuda., Sci. Rep. Tohoku Imp. Univ., 18,323 (1929) Chi, Kao, Chang.,i. Amer. Chern. Soc., 58, 1306 (1936) Chi, Kao, Chang., ibid, 62, 1778 (1944)

Properties of Peimine

Melting point: 223-224°
Boiling point: 568.4±50.0 °C(Predicted)
alpha  D16 -19.4° (ethanol); D17 -20° (CHCl3)
Density  1.18±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  Acetonitrile (Slightly, Heated, Sonicated), Chloroform (Slightly), Ethanol (Slig
form  Solid
pka 9.5(at 25℃)
color  White to Off-White

Safety information for Peimine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for Peimine

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