PAROXETINE-D4 HCL

Synonym(s):(3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate;5-HT transporter, Paroxetine, Paxil;Paroxetine HCl;Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem

CAS NO.：110429-35-1
Empirical Formula: C19H23ClFNO4
Molecular Weight: 383.84
MDL number: MFCD00797405
EINECS: 000-000-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 20:33:22

What is PAROXETINE-D4 HCL?

Chemical properties

White or almost white, crystalline powder.

The Uses of PAROXETINE-D4 HCL

Paroxetine hydrochloride hemihydrate has been used: as an antidepressant to study its effects on neural stem cells (NSCs) from embryonic rat hippocampus in vitro; as a CYP 2D6 inhibitor to study its effects on the in vitro?production by human recombinant CYP 2D6 of the phenolic metabolites; as an antidepressant to study its effects on the expression of pituitary adenylate cyclase activating polypeptide (PACAP), its receptors and brain-derived neurotrophic factor (BDNF) in rat primary hippocampal neurons

The Uses of PAROXETINE-D4 HCL

Antidepressant;5-HT uptake inhibitor

The Uses of PAROXETINE-D4 HCL

Paroxetine Hydrochloride, is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

General Description

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Biochem/physiol Actions

Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant

Properties of PAROXETINE-D4 HCL

Melting point:	121-131 C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	Slightly soluble in water, freely soluble in methanol, sparingly soluble in ethanol (96 per cent) and in methylene chloride.
form	powder
color	white
λmax	292nm(H2O)(lit.)
Merck	14,7043
CAS DataBase Reference	110429-35-1

Safety information for PAROXETINE-D4 HCL

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.