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HomeProduct name listPiperidine hydrochloride

Piperidine hydrochloride

  • CAS NO.:6091-44-7
  • Empirical Formula: C5H11N.ClH
  • Molecular Weight: 121.61
  • MDL number: MFCD00012770
  • EINECS: 228-033-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-20 14:01:34
Piperidine hydrochloride Structural

What is Piperidine hydrochloride?

Chemical properties

WHITE FINE CRYSTALLINE POWDER

The Uses of Piperidine hydrochloride

Piperidine hydrochloride is used an intermediate in the manufacture of active pharmaceutical ingredients like anti Parkinsonan agent Biperiden; anti depressant agent Clocapramine hydrochloride and muscle relaxant tolperisone.

The Uses of Piperidine hydrochloride

Reagent for synthesis of:

  • Quinoline selenium compounds
  • Peripheral seratonin 5-HT3 receptor ligands

Reactant for synthesis of phthalazinone derivatives as topically active phosphodiesterase 4 inhibitors

Reactant for:
  • Mannich reactions
  • Asymmetric hydrogenation of quinolines
  • Chemoselective reductive amination of carbonyl compounds

Purification Methods

Crystallise the salt from EtOH/diethyl ether in the presence of a small amount of HCl. [Beilstein 20 H 6, 20 II 10, 20 III/IV 295, 20/2 V 13.]

Properties of Piperidine hydrochloride

Melting point: 245-248 °C(lit.)
Boiling point: 347.05℃
Density  1,12 g/cm3
vapor density  2.94 (vs air)
vapor pressure  63.6 mm Hg ( 37.8 °C)
Flash point: >230 °F
storage temp.  Store below +30°C.
solubility  >1500g/l
form  Solid:crystalline
PH 6-8 (111g/l, H2O, 20℃)
Water Solubility  soluble
Sensitive  Hygroscopic
BRN  3611699
CAS DataBase Reference 6091-44-7(CAS DataBase Reference)
EPA Substance Registry System Piperidine hydrochloride (6091-44-7)

Safety information for Piperidine hydrochloride

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H301:Acute toxicity,oral
Precautionary Statement Codes P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for Piperidine hydrochloride

InChIKey VEIWYFRREFUNRC-UHFFFAOYSA-N

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