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HomeProduct name listPARAOXON

PARAOXON

Synonym(s):O,O-Diethyl O-(4-nitrophenyl) phosphate;Diethyl p-nitrophenyl phosphate;Paraoxon;Paraoxon-ethyl

  • CAS NO.:311-45-5
  • Empirical Formula: C10H14NO6P
  • Molecular Weight: 275.2
  • MDL number: MFCD00007316
  • EINECS: 206-221-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:30
PARAOXON Structural

What is PARAOXON?

Chemical properties

Oily Liquid

Chemical properties

Paraoxon is an odorless, reddish-yellow oil. Fruity odor.

The Uses of PARAOXON

Paraoxon-ethyl has been used as a substrate?in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein?L3 (HDL3)?to?HDL2?in vivo.

The Uses of PARAOXON

A cholinesterase inhibitor

The Uses of PARAOXON

Insecticide.

What are the applications of Application

Paraoxon is an organophosphate pesticide, parathion metabolite, and acetylcholinesterase inhibitor.

Definition

ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6

General Description

Reddish-yellow oily liquid with a faint fruity odor.

Reactivity Profile

Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Fire Hazard

Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.

Biochem/physiol Actions

Potent irreversible acetylcholinesterase inhibitor

Safety Profile

A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos

Potential Exposure

An organophosphate insecticide. Has been used as a medication.

Shipping

UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.

Incompatibilities

Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.

Waste Disposal

In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.

Properties of PARAOXON

Melting point: 300°C
Boiling point: 169-170°C
Density  1.274 g/mL at 25 °C(lit.)
refractive index  n20/D 1.51(lit.)
storage temp.  2-8°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  oil
color  yellow
Odor slt odor
Water Solubility  3.627g/L(20 ºC)
Merck  13,7102
BRN  1915526
Stability: Moisture Sensitive
CAS DataBase Reference 311-45-5
EPA Substance Registry System Paraoxon (311-45-5)

Safety information for PARAOXON

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Environment
GHS09
GHS Hazard Statements H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P262:Do not get in eyes, on skin, or on clothing.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for PARAOXON

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