PARAOXON
Synonym(s):O,O-Diethyl O-(4-nitrophenyl) phosphate;Diethyl p-nitrophenyl phosphate;Paraoxon;Paraoxon-ethyl
- CAS NO.:311-45-5
- Empirical Formula: C10H14NO6P
- Molecular Weight: 275.2
- MDL number: MFCD00007316
- EINECS: 206-221-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:43:30
What is PARAOXON?
Chemical properties
Oily Liquid
Chemical properties
Paraoxon is an odorless, reddish-yellow oil. Fruity odor.
The Uses of PARAOXON
Paraoxon-ethyl has been used as a substrate?in paraoxonase (PON) activity assay. It has also been used as a lipase inhibitor to study the effects of anacetrapib on homotypic transfer from high density lipoprotein?L3 (HDL3)?to?HDL2?in vivo.
The Uses of PARAOXON
A cholinesterase inhibitor
The Uses of PARAOXON
Insecticide.
What are the applications of Application
Paraoxon is an organophosphate pesticide, parathion metabolite, and acetylcholinesterase inhibitor.
Definition
ChEBI: An aryl dialkyl phosphate where both the alkyl groups are ethyl and the aryl group is 4-nitrophenyl.
Synthesis Reference(s)
Tetrahedron Letters, 31, p. 3359, 1990 DOI: 10.1016/S0040-4039(00)89065-6
General Description
Reddish-yellow oily liquid with a faint fruity odor.
Reactivity Profile
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Fire Hazard
Flash point data for PARAOXON are not available; however, PARAOXON is probably combustible.
Biochem/physiol Actions
Potent irreversible acetylcholinesterase inhibitor
Safety Profile
A deadly poison by ingestion,intraperitoneal, intravenous, subcutaneous, intramuscular,and parenteral routes. Mutation data reported. Humansystemic effects: coma, convulsions, miosis. Acholinesterase inhibitor. An insecticide. When heated todecompos
Potential Exposure
An organophosphate insecticide. Has been used as a medication.
Shipping
UN3018 Organophosphorus pesticides, liquid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
Incompatibilities
Keep away from alkaline materials and strong oxidizers. Contact with oxidizers can cause the release of toxic oxides of phosphorus. May react violently with antimony(V) pentafluoride. Incompatible with lead diacetate, magnesium, silver nitrate. In the presence of strong reducing agents such as hydrides, organophosphates form highly toxic and flammable phosphine gas.
Waste Disposal
In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
Properties of PARAOXON
Melting point: | 300°C |
Boiling point: | 169-170°C |
Density | 1.274 g/mL at 25 °C(lit.) |
refractive index | n |
storage temp. | 2-8°C |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
form | oil |
color | yellow |
Odor | slt odor |
Water Solubility | 3.627g/L(20 ºC) |
Merck | 13,7102 |
BRN | 1915526 |
Stability: | Moisture Sensitive |
CAS DataBase Reference | 311-45-5 |
EPA Substance Registry System | Paraoxon (311-45-5) |
Safety information for PARAOXON
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Environment GHS09 |
GHS Hazard Statements |
H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P262:Do not get in eyes, on skin, or on clothing. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for PARAOXON
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